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Table 5 Sensitivity analysis for projected savings over 20 years with DOTS expansion in Haiti

From: Impact of DOTS expansion on tuberculosis related outcomes and costs in Haiti

    SAVINGS in $US MILLIONS WITH DOTS EXPANSION *
    PERSPECTIVE  
PARAMETER VARIED CHANGE NEW VALUE SOCIETAL GOVERNMENT
Base Case (from Table 4) Base Base ($131) ($4)
Initial DOTS investment Double $8.4 million total ($126) ($0)
Annual DOTS maintenance Double $722,000 per year ($128) ($1)
Annual DOTS maintenance + cost of TB drugs Double both $847,900 per year ($128) ($1)
Foreign Donor Pays: Initial + annual + TB drugs Eliminate all three $8.44 million + $847,000 per year ($138) ($11)
Change average duration of hospitalization Decrease with DOTS, increase with Non-DOTS 3 days – DOTS 60 days non-DOTS ($165) ($29)
Single (SDR) and Multi (MDR) Drug resistance Double prevalence of drug resistance SDR : 40% MDR : 0.6% ($131) ($4)
Impact of DOTS expansion on TB incidence in subsequent years None
1/3 of base
2/3 of base
0% annual decline
2% annual decline
4% annual decline
($61)
($88)
($111)
$ 14 *
$ 7*
$ 1*
  1. Notes:
  2. * A number in parentheses indicates net societal or government savings, while a number not in parentheses indicates a net increased cost with DOTS expansion,.