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Table 5 Program performance. The incremental cost-effectiveness of evaluation and treatment of disease among a hypothetical cohort of 1000 B-notification patients followed for 20 years. The table presents the outcomes of a decision to treat individuals in ATS class TB2, listing the number of QALYs averted, the net cost, the number of cases averted, and the difference in the number of deaths among individuals with tuberculosis with and without the program, for various levels of the evaluation rate, the starting rate, and the completion rate. All outcomes are discounted at a rate of three percent per year. Each row is computed by averaging 10 000 replications of a cohort of 1 000 individuals each, over a 20-year period; standard errors are given in parentheses.

From: Cost-effectiveness of tuberculosis evaluation and treatment of newly-arrived immigrants

Evaluation Rate

Starting Rate

Completion Rate

QALYs saved

Net costs (1000s)

Cases Averted

TB Deaths Averted

45%

35%

30%

0.12 (0.08)

0.022 (0.4)

0.2 (0.02)

0.0073 (0.005)

45%

35%

55%

0.22 (0.1)

0.43 (0.4)

0.2 (0.02)

0.011 (0.006)

45%

35%

75%

0.25 (0.07)

0.09 (0.5)

0.23 (0.02)

0.013 (0.004)

45%

45%

30%

0.17 (0.08)

0.34 (0.2)

0.2 (0.02)

0.013 (0.004)

45%

45%

55%

0.32 (0.06)

0.86 (0.4)

0.24 (0.02)

0.016 (0.002)

45%

45%

75%

0.23 (0.06)

1.1 (0.6)

0.28 (0.02)

0.011 (0.003)

45%

80%

30%

0.35 (0.1)

1.4 (0.5)

0.33 (0.02)

0.014 (0.006)

45%

80%

55%

0.42 (0.1)

2.3 (0.5)

0.4 (0.02)

0.018 (0.005)

45%

80%

75%

0.55 (0.06)

2.4 (0.4)

0.45 (0.02)

0.025 (0.004)

65%

35%

30%

0.21 (0.07)

0.24 (0.4)

0.21 (0.02)

0.01 (0.003)

65%

35%

55%

0.1 (0.07)

1.3 (0.4)

0.25 (0.02)

0.0025 (0.004)

65%

35%

75%

0.28 (0.07)

1.9 (0.2)

0.29 (0.01)

0.016 (0.004)

65%

45%

30%

0.26 (0.08)

1.1 (0.4)

0.27 (0.01)

0.01 (0.005)

65%

45%

55%

0.44 (0.07)

0.87 (0.4)

0.36 (0.03)

0.019 (0.003)

65%

45%

75%

0.62 (0.06)

1.7 (0.4)

0.42 (0.02)

0.026 (0.004)

65%

80%

30%

0.51 (0.04)

1.6 (0.3)

0.49 (0.01)

0.024 (0.003)

65%

80%

55%

0.72 (0.09)

1.9 (0.5)

0.64 (0.03)

0.035 (0.004)

65%

80%

75%

0.64 (0.07)

3.7 (0.3)

0.69 (0.03)

0.028 (0.003)

85%

35%

30%

0.34 (0.08)

1 (0.4)

0.3 (0.02)

0.015 (0.004)

85%

35%

55%

0.34 (0.1)

1.4 (0.5)

0.32 (0.02)

0.014 (0.004)

85%

35%

75%

0.29 (0.07)

2.4 (0.5)

0.37 (0.02)

0.013 (0.004)

85%

45%

30%

0.37 (0.07)

1 (0.5)

0.36 (0.02)

0.016 (0.004)

85%

45%

55%

0.36 (0.05)

2.4 (0.6)

0.43 (0.02)

0.015 (0.003)

85%

45%

75%

0.49 (0.08)

3 (0.6)

0.46 (0.03)

0.022 (0.005)

85%

80%

30%

0.59 (0.07)

2 (0.3)

0.66 (0.02)

0.026 (0.002)

85%

80%

55%

0.77 (0.09)

3.9 (0.5)

0.79 (0.02)

0.034 (0.003)

85%

80%

75%

0.85 (0.06)

5.3 (0.4)

0.85 (0.02)

0.036 (0.003)