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Early SES → Outcome
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Early-life SES variable(s) used to predict CVD (e.g., CHD, stroke). Adjusted for later-life events, behaviors, risk factor levels to determine "direct" effect of early life SES.
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Is there a significant independent effect of early-life (childhood) SES on the adult risk of CVD after adjusting for later-life SES and risk factors?
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Early SES → Risk Factor
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Early-life SES variable(s) used to predict adult CVD risk factors levels.
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How does early-life SES affect later-life levels of behavioral and physiological CVD risk factors?
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Social Trajectory
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Inter- or intragenerational movement from one SES level to another (i.e., Low SES to High SES) used to predict adult CVD risk factors levels or CVD outcomes.
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How does social mobility from one point to another during the life course affect the risk of CVD?
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Cumulative SES
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A summary variable indicating number of negative SES events/environments over the life course used to predict adult CVD risk factors levels or CVD outcomes.
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How does the accumulated number of negative SES-related exposures across the life course influence the risk of CVD?
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