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Table 1 Numbers of newborns, children with Down syndrome, and prevalence rates of Down syndrome, California (1996–97) and the Czech Republic (1994–98)

From: Down syndrome, paternal age and education: comparison of California and the Czech Republic

  California Czech Republic
  All children Children with DS All children Children with DS
  No. % of births No. % of births Prevalence per 10 000 No. % of births No. % of births Prevalence per 10 000
Sex of infants           
Boy 264 321 51.2 328 55.3 12.4 244 503 51.4 144 57.4 5.9
Girl 252 408 48.8 265 44.7 10.5 231 331 48.6 107 42.6 4.6
Unknown 16   0    0   0   
Education of mother           
Primary 85 615 16.6 157 26.5 18.3 64 774 13.6 34 13.5 5.2
Vocational 107 633 20.8 96 16.2 8.9 199 260 41.9 110 43.8 5.5
Secondary 234 312 45.3 251 42.3 10.7 168 659 35.4 80 31.9 4.7
University 83 681 16.2 77 13.0 9.2 43 135 9.1 27 10.8 6.3
Unknown 5 504   12    6   0   
Maternal age           
-19 65 058 12.6 31 5.2 4.8 46 236 9.7 17 6.8 3.7
20–22 73 102 14.1 46 7.8 6.3 118 195 24.8 57 22.7 4.8
23–25 79 444 15.4 55 9.3 6.9 121 827 25.6 50 19.9 4.1
26–28 83 791 16.2 56 9.4 6.7 85 173 17.9 40 15.9 4.7
29–31 78 435 15.2 64 10.8 8.2 52 998 11.1 28 11.2 5.3
32–34 64 442 12.5 101 17.0 15.7 28 689 6.0 27 10.8 9.4
35–37 42 301 8.2 75 12.6 17.7 14 171 3.0 14 5.6 9.9
38–40 21 289 4.1 83 14.0 39.0 6 431 1.4 7 2.8 10.9
41–43 7 173 1.4 68 11.5 94.8 1 818 0.4 6 2.4 33.0
44+ 1 527 0.3 14 2.4 91.7 296 0.1 5 2.0 168.9
Unknown 183   0    0   0   
Paternal age           
-19 24 635 4.8 14 2.4 5.7 6 670 1.4 3 1.2 4.5
20–22 47 498 9.2 30 5.1 6.3 49 493 10.4 14 5.6 2.8
23–25 64 126 12.4 41 6.9 6.4 87 675 18.4 43 17.1 4.9
26–28 74 838 14.5 54 9.1 7.2 88 677 18.6 41 16.3 4.6
29–31 75 282 14.6 82 13.8 10.9 68 831 14.5 29 11.6 4.2
32–34 69 024 13.4 76 12.8 11.0 42 989 9.0 24 9.6 5.6
35–37 51 791 10.0 75 12.6 14.5 23 953 5.0 21 8.4 8.8
38–40 32 849 6.4 46 7.8 14.0 14 105 3.0 14 5.6 9.9
41–43 18 406 3.6 66 11.1 35.9 7 402 1.6 7 2.8 9.5
44+ 18 286 3.5 66 11.1 36.1 6 610 1.4 9 3.6 13.6
Unknown 40 010   43    79 429   46   
Total 516 745 100 593 100 11.5 475 834 100 251 100 5.3