Table 1 Numbers of newborns, children with Down syndrome, and prevalence rates of Down syndrome, California (1996–97) and the Czech Republic (1994–98)
From: Down syndrome, paternal age and education: comparison of California and the Czech Republic
| Â | California | Czech Republic | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Â | All children | Children with DS | All children | Children with DS | ||||||
| Â | No. | % of births | No. | % of births | Prevalence per 10 000 | No. | % of births | No. | % of births | Prevalence per 10 000 |
Sex of infants | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Boy | 264 321 | 51.2 | 328 | 55.3 | 12.4 | 244 503 | 51.4 | 144 | 57.4 | 5.9 |
Girl | 252 408 | 48.8 | 265 | 44.7 | 10.5 | 231 331 | 48.6 | 107 | 42.6 | 4.6 |
Unknown | 16 | Â | 0 | Â | Â | 0 | Â | 0 | Â | Â |
Education of mother | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Primary | 85 615 | 16.6 | 157 | 26.5 | 18.3 | 64 774 | 13.6 | 34 | 13.5 | 5.2 |
Vocational | 107 633 | 20.8 | 96 | 16.2 | 8.9 | 199 260 | 41.9 | 110 | 43.8 | 5.5 |
Secondary | 234 312 | 45.3 | 251 | 42.3 | 10.7 | 168 659 | 35.4 | 80 | 31.9 | 4.7 |
University | 83 681 | 16.2 | 77 | 13.0 | 9.2 | 43 135 | 9.1 | 27 | 10.8 | 6.3 |
Unknown | 5 504 | Â | 12 | Â | Â | 6 | Â | 0 | Â | Â |
Maternal age | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
-19 | 65 058 | 12.6 | 31 | 5.2 | 4.8 | 46 236 | 9.7 | 17 | 6.8 | 3.7 |
20–22 | 73 102 | 14.1 | 46 | 7.8 | 6.3 | 118 195 | 24.8 | 57 | 22.7 | 4.8 |
23–25 | 79 444 | 15.4 | 55 | 9.3 | 6.9 | 121 827 | 25.6 | 50 | 19.9 | 4.1 |
26–28 | 83 791 | 16.2 | 56 | 9.4 | 6.7 | 85 173 | 17.9 | 40 | 15.9 | 4.7 |
29–31 | 78 435 | 15.2 | 64 | 10.8 | 8.2 | 52 998 | 11.1 | 28 | 11.2 | 5.3 |
32–34 | 64 442 | 12.5 | 101 | 17.0 | 15.7 | 28 689 | 6.0 | 27 | 10.8 | 9.4 |
35–37 | 42 301 | 8.2 | 75 | 12.6 | 17.7 | 14 171 | 3.0 | 14 | 5.6 | 9.9 |
38–40 | 21 289 | 4.1 | 83 | 14.0 | 39.0 | 6 431 | 1.4 | 7 | 2.8 | 10.9 |
41–43 | 7 173 | 1.4 | 68 | 11.5 | 94.8 | 1 818 | 0.4 | 6 | 2.4 | 33.0 |
44+ | 1 527 | 0.3 | 14 | 2.4 | 91.7 | 296 | 0.1 | 5 | 2.0 | 168.9 |
Unknown | 183 | Â | 0 | Â | Â | 0 | Â | 0 | Â | Â |
Paternal age | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
-19 | 24 635 | 4.8 | 14 | 2.4 | 5.7 | 6 670 | 1.4 | 3 | 1.2 | 4.5 |
20–22 | 47 498 | 9.2 | 30 | 5.1 | 6.3 | 49 493 | 10.4 | 14 | 5.6 | 2.8 |
23–25 | 64 126 | 12.4 | 41 | 6.9 | 6.4 | 87 675 | 18.4 | 43 | 17.1 | 4.9 |
26–28 | 74 838 | 14.5 | 54 | 9.1 | 7.2 | 88 677 | 18.6 | 41 | 16.3 | 4.6 |
29–31 | 75 282 | 14.6 | 82 | 13.8 | 10.9 | 68 831 | 14.5 | 29 | 11.6 | 4.2 |
32–34 | 69 024 | 13.4 | 76 | 12.8 | 11.0 | 42 989 | 9.0 | 24 | 9.6 | 5.6 |
35–37 | 51 791 | 10.0 | 75 | 12.6 | 14.5 | 23 953 | 5.0 | 21 | 8.4 | 8.8 |
38–40 | 32 849 | 6.4 | 46 | 7.8 | 14.0 | 14 105 | 3.0 | 14 | 5.6 | 9.9 |
41–43 | 18 406 | 3.6 | 66 | 11.1 | 35.9 | 7 402 | 1.6 | 7 | 2.8 | 9.5 |
44+ | 18 286 | 3.5 | 66 | 11.1 | 36.1 | 6 610 | 1.4 | 9 | 3.6 | 13.6 |
Unknown | 40 010 | Â | 43 | Â | Â | 79 429 | Â | 46 | Â | Â |
Total | 516 745 | 100 | 593 | 100 | 11.5 | 475 834 | 100 | 251 | 100 | 5.3 |