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Table 2 Course of outcome parameters and estimated mean changes of outcome parameters

From: Homeopathic medical practice: Long-term results of a cohort study with 3981 patients

      Estimated changes compared to baseline†
  Baseline 3 months 12 months 24 month Δ 3 months Δ 12 months Δ 24 months
  mean ± SD mean ± SD mean ± SD mean ± SD mean (95%CI) mean (95%CI) mean (95%CI)
Adults
   Patients assessments (NRS) ‡ 6.2 ± 1.7 3.8 ± 2.2* 3.3 ± 2.1* 2.9 ± 2.2* -2.4 (-2.5 to -2.3) -2.8 (-2.9 to -2.7) -3.1 (-3.2 to -3.0)
   Physicians assessments (NRS) ‡ 6.0 ± 1.6 3.9 ± 2.1* 2.8 ± 2.1* 2.1 ± 2.0* -2.1 (-2.2 to -2.0) -3.1 (-3.2 to -3.0) -3.7 (-3.8 to -3.6)
   SF-36 QoL physical scale 46.5 ± 10.1 49.1 ± 9.5* 50.1 ± 9.6* 50.7 ± 9.5* 2.6 (2.3 to 2.9) 3.5 (3.0 to 3.9) 4.1 (3.5 to 4.6)
   SF-36 QoL mental scale 39.3 ± 11.8 44.6 ± 10.8* 45.5 ± 10.8* 46.4 ± 10.6* 5.6 (5.2 to 6.0) 6.2 (5.7 to 6.7) 6.9 (6.3 to 7.6)
Children
   Patients assessments (NRS) ‡ 6.1 ± 1.8 3.2 ± 2.3* 2.5 ± 2.1* 2.2 ± 2.0* -3.1 (-3.3 to -2.9) -3.5 (-3.7 to -3.4) -3.9 (-4.0 to -3.7)
   Physicians assessments (NRS) ‡ 5.9 ± 1.7 3.2 ± 2.2* 2.0 ± 1.5* 1.5 ± 1.8* -2.7 (-2.8 to -2.6) -3.8 (-4.0 to -3.7) -4.4 (-4.6 to -4.3)
   KINDL QoL 69.3 ± 13.3 72.1 ± 12.6 68.0 ± 9.2 67.3 ± 9.9* 2.7 (1.7 to 3.7) -0.4 (-1.5 to 0.8) -2.2 (-3.6 to -0.8)
   KITA QoL mental/physical dimension 67.6 ± 16.9 75.4 ± 14.6* 77.0 ± 14.1* 77.5 ± 14.3* 8.3 (6.6 to 10.0) 9.3 (7.7 to 10.8) 10.0 (8.3 to 11.6)
   KITA QoL aspects of daily living 58.6 ± 18.3 66.9 ± 15.9* 69.1 ± 16.7* 70.6 ± 16.0* 8.5 (7.2 to 9.8) 10.4 (8.8 to 12.0) 11.6 (9.7 to 13.5)
  1. † estimations are based on generalised linear models, see text; ‡ = lower values indicate better status and negative Δ indicates improvement
  2. QoL = quality of life; NRS = numeric rating scale, * p < 0.001 versus baseline