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Table 2 Course of outcome parameters and estimated mean changes of outcome parameters

From: Homeopathic medical practice: Long-term results of a cohort study with 3981 patients

     

Estimated changes compared to baseline†

 

Baseline

3 months

12 months

24 month

Δ 3 months

Δ 12 months

Δ 24 months

 

mean ± SD

mean ± SD

mean ± SD

mean ± SD

mean (95%CI)

mean (95%CI)

mean (95%CI)

Adults

   Patients assessments (NRS) ‡

6.2 ± 1.7

3.8 ± 2.2*

3.3 ± 2.1*

2.9 ± 2.2*

-2.4 (-2.5 to -2.3)

-2.8 (-2.9 to -2.7)

-3.1 (-3.2 to -3.0)

   Physicians assessments (NRS) ‡

6.0 ± 1.6

3.9 ± 2.1*

2.8 ± 2.1*

2.1 ± 2.0*

-2.1 (-2.2 to -2.0)

-3.1 (-3.2 to -3.0)

-3.7 (-3.8 to -3.6)

   SF-36 QoL physical scale

46.5 ± 10.1

49.1 ± 9.5*

50.1 ± 9.6*

50.7 ± 9.5*

2.6 (2.3 to 2.9)

3.5 (3.0 to 3.9)

4.1 (3.5 to 4.6)

   SF-36 QoL mental scale

39.3 ± 11.8

44.6 ± 10.8*

45.5 ± 10.8*

46.4 ± 10.6*

5.6 (5.2 to 6.0)

6.2 (5.7 to 6.7)

6.9 (6.3 to 7.6)

Children

   Patients assessments (NRS) ‡

6.1 ± 1.8

3.2 ± 2.3*

2.5 ± 2.1*

2.2 ± 2.0*

-3.1 (-3.3 to -2.9)

-3.5 (-3.7 to -3.4)

-3.9 (-4.0 to -3.7)

   Physicians assessments (NRS) ‡

5.9 ± 1.7

3.2 ± 2.2*

2.0 ± 1.5*

1.5 ± 1.8*

-2.7 (-2.8 to -2.6)

-3.8 (-4.0 to -3.7)

-4.4 (-4.6 to -4.3)

   KINDL QoL

69.3 ± 13.3

72.1 ± 12.6

68.0 ± 9.2

67.3 ± 9.9*

2.7 (1.7 to 3.7)

-0.4 (-1.5 to 0.8)

-2.2 (-3.6 to -0.8)

   KITA QoL mental/physical dimension

67.6 ± 16.9

75.4 ± 14.6*

77.0 ± 14.1*

77.5 ± 14.3*

8.3 (6.6 to 10.0)

9.3 (7.7 to 10.8)

10.0 (8.3 to 11.6)

   KITA QoL aspects of daily living

58.6 ± 18.3

66.9 ± 15.9*

69.1 ± 16.7*

70.6 ± 16.0*

8.5 (7.2 to 9.8)

10.4 (8.8 to 12.0)

11.6 (9.7 to 13.5)

  1. † estimations are based on generalised linear models, see text; ‡ = lower values indicate better status and negative Δ indicates improvement
  2. QoL = quality of life; NRS = numeric rating scale, * p < 0.001 versus baseline