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Table 3 Benefits and drug costs over 1-year for a practice population of 10,000 resulting from the introduction of these treatments assuming the total benefit of the drugs

From: Implementing guidelines in primary care: can population impact measures help?

  

Number Needed to Treat (NNT)

Disease Impact Number (DIN)

Population Impact Number (PIN)

Number to be Treated in your Population (NTP)

Number of Events Prevented in your Population (NEPP)

Total drug cost (€)

Drug cost per death prevented (€)

MI

ACE-I

       
 

ACE-I

69

93

1,653

147

2.12

14,700

6,944

 

BB

48

64

1,150

147

3.04

6,615

2,174

 

Statin

53

66

1,181

157

2.96

60,525

20,423

 

Aspirin

93

103

1,837

176

1.91

1,940

1,019

MI + CHF

        
 

ACE-I

23

31

5,109

16

0.69

1,575

2,299

 

BB

16

22

3,649

16

0.96

709

739

 

Spironolactone

11

15

2,554

16

1.37

2,268

1,655

  1. MI myocardial Infarction CHF Heart Failure ACE-I ACE Inhibitor BB beta blocker