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Table 3 Benefits and drug costs over 1-year for a practice population of 10,000 resulting from the introduction of these treatments assuming the total benefit of the drugs

From: Implementing guidelines in primary care: can population impact measures help?

   Number Needed to Treat (NNT) Disease Impact Number (DIN) Population Impact Number (PIN) Number to be Treated in your Population (NTP) Number of Events Prevented in your Population (NEPP) Total drug cost (€) Drug cost per death prevented (€)
MI ACE-I        
  ACE-I 69 93 1,653 147 2.12 14,700 6,944
  BB 48 64 1,150 147 3.04 6,615 2,174
  Statin 53 66 1,181 157 2.96 60,525 20,423
  Aspirin 93 103 1,837 176 1.91 1,940 1,019
MI + CHF         
  ACE-I 23 31 5,109 16 0.69 1,575 2,299
  BB 16 22 3,649 16 0.96 709 739
  Spironolactone 11 15 2,554 16 1.37 2,268 1,655
  1. MI myocardial Infarction CHF Heart Failure ACE-I ACE Inhibitor BB beta blocker