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Table 2 Risk of pancreatic cancer in association with aspirin use – Roswell Park Cancer Institute, Buffalo, NY 1982–1996.

From: Regular use of aspirin and pancreatic cancer risk

  Cases n (%) Controls n (%) Crude OR (95% CI) Adjusted OR1 (95% CI)
All
Non-Regular User 108(55.7) 327(56.2) 1.00 1.00
Regular User2 86 (44.3) 255(43.8) 1.02 (0.74, 1.42) 1.00 (0.72, 1.39)
Dosage Used     
   1–6 tabs/wk3 61 (31.4) 157(26.9) 1.18 (0.82, 1.70) 1.15 (0.79, 1.67)
   7+ tabs/wk3 25 (12.9) 98 (16.8) 0.87 (0.51, 1.48) 0.85 (0.49, 1.45)
Duration of Use     
   0.5–10 years3 37 (19.1) 137(23.6) 0.82 (0.54, 1.25) 0.82 (0.54, 1.26)
   11+ years3 49 (25.3) 117(20.1) 1.27 (0.85, 1.89) 1.21 (0.81, 1.82)
Tablet-years of Use3     
   1–10 tablet years 69 (35.6) 176 (30.2) 1.19 (0.83, 1.69) 1.15 (0.80, 1.65)
   11+ tablet years 17 (8.8) 79 (13.6) 0.65 (0.37, 1.15) 0.65 (0.37, 1.16)
Men
Non-Regular User 58 (54.7) 174 (54.7) 1.00 1.00
Regular User2 48 (45.3) 144 (45.2) 1.00 (0.64, 1.56) 0.99 (0.64, 1.5)
Dosage Used3     
   1–6 tabs/wk 31 (29.2) 87 (27.4) 1.07 (0.64, 1.77) 1.05 (0.63, 1.75)
   7+ tabs/wk 17 (16.0) 57 (17.9) 0.90 (0.48, 1.66) 0.91 (0.49, 1.70)
Duration of Use3     
   0.5–10 years 27 (25.5) 81 (25.5) 1.00 (0.59, 1.69) 1.03 (0.60, 1.75)
   11+ years 21 (19.8) 63 (19.8) 1.00 (0.56, 1.78) 0.95 (0.53, 1.72)
Tablet-years of Use3     
   1–10 tablet years 43 (40.6) 113 (35.5) 1.14 (0.72, 1.81) 1.12 (0.70, 1.78)
   11+ tablet years 5 (4.7) 31 (9.7) 0.48 (0.18, 1.30) 0.52 (0.19, 1.40)
Women
Non-Regular User 50 (56.8) 153 (59.0) 1.00 1.00
Regular User2 38 (43.2) 111 (42.0) 1.05 (0.64, 1.71) 1.01 (0.62, 1.67)
Dosage Used3     
   1–6 tabs/wk 30 (34.1) 70 (26.5) 1.31 (0.77, 2.24) 1.29 (0.75, 2.23)
   7+ tabs/wk 4 (9.1) 41 (15.5) 0.77 (0.24, 2.40) 0.67 (0.21, 2.14)
Duration of Use3     
   0.5–10 years 10 (11.4) 56 (21.2) 0.55 (0.26, 1.15) 0.55 (0.26, 1.16)
   11+ years 28 (31.8) 54 (20.5) 1.59 (0.91, 2.77) 1.52 (0.86, 2.69)
Tablet-years of Use3     
   1–10 tablet years 26 (29.5) 63 (23.9) 1.26 (0.72, 2.21) 1.25 (0.70, 2.20)
   11+ tablet years 12 (13.6) 48 (18.2) 0.77 (0.38, 1.55) 0.72 (0.35, 1.49)
  1. 1. Odds ratio adjusted for age, packyears of smoking and family history of pancreatic cancer. 2. Regular use defined as self-reported use for at least once a week for six consecutive months. 3. Among regular users.