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Table 1 Serodiscordant couples sample size calculations

From: The Opposites Attract Study of viral load, HIV treatment and HIV transmission in serodiscordant homosexual male couples: design and methods

Percentage of HIV men who are on ART and have undetectable BPVL

Reduction in HIV incidence in HIV-negative men with partners with undetectable BPVL

Required number of HIV seroconversion events

Total sample size required

60%

0.75

18

631

 

0.85

11

436

 

0.95

7

305

70%

0.75

15

624

 

0.85

9

413

 

0.95

5

272

80%

0.75

14

692

 

0.85

7

429

 

0.95

4

256

90%

0.75

17

1008

 

0.85

7

563

 

0.95

3

276