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Table 1 Characteristics of the participants and data on exposure, renal markers and prevalence of illness grouped according to area and gender

From: Risk assessment for Thai population: benchmark dose of urinary and blood cadmium levels for renal effects by hybrid approach of inhabitants living in polluted and non-polluted areas in Thailand

  

Non-polluted area

Polluted area

Total

Age groups (yrs)

 

40-49

50-59

60-69

≥70

Total

40-49

50-59

60-69

≥70

Total

40-49

50-59

60-69

≥70

Total

Men

N

9

9

12

10

40

71

52

54

53

230

80

61

66

64

270

Age (yrs)

M (SD)

44.5 (2.8)

54.6 (3.1)

64.6 (2.9)

76.4 (4.9)

61.1 (12.4)

44.1 (2.7)

52.0 (3.2)

63.7 (2.7)

75.6 (4.4)

55.6 (14.0)

44.5 (2.7)

54.2 (3.2)

63.9 (2.8)

75.7 (4.5)

56.3 (13.9)

Urinary Cd (μg/g Creat)

GM (GSD)

0.4 (2.5)

0.5 (2.1)

0.7 (1.4)

0.5 (1.8)

0.5 (1.9)

5.9 (1.8)

7.0 (2.0)

6.9 (1.7)

6.3 (2.0)

6.3 (1.9)

4.4 (2.9)

4.8 (3.3)

4.5 (2.8)

4.1 (3.2)

4.5 (2.9)

Blood cadmium (μg/L)

GM (GSD)

0.9 (2.7)

0.7 (2.5)

1.0 (1.8)

0.9 (2.0)

0.9 (2.2)

6.1 (1.9)

6.7 (1.9)

7.8 (1.8)

7.3 (1.8)

6.9 (1.9)

4.9 (2.5)

4.9 (2.8)

5.4 (2.7)

5.1 (2.7)

5.1 (2.7)

ß2-MG (μg/g Creat)

GM (GSD)

133 (2.2)

124 (3.4)

214 (3.6)

832 (3.5)

249.6 (4.0)

101 (3.6)

500 (8.9)

567 (8.6)

2221 (11.3)

443.3 (9.9)

104 (3.5)

407 (8.4)

475 (7.8)

1876 (9.8)

407.2 (9.0)

NAG (IU/g Creat)

GM (GSD)

3.3 (1.6)

5.5 (2.2)

4.7 (1.7)

8.0 (2.5)

5.2 (2.1)

4.2 (1.7)

5.3 (1.9)

6.1 (1.7)

7.9 (1.7)

5.3 (1.9)

4.1 (1.7)

5.4 (2.0)

5.8 (1.7)

7.9 (1.8)

5.3 (1.9)

Smoking habit

                

 Ex-smokers

%

44.4

55.6

45.5

36.4

45.0

25.4

28.8

35.2

54.7

31.2

27.5

32.8

36.9

51.6

33.0

 Smokers

%

44.4

44.4

36.4

36.4

40.0

67.6

67.3

61.1

41.5

53.1

65

63.9

56.9

40.6

51.3

Prevalence of illness

                

 Hypertension

%

22.2

22.2

41.7

36.4

32.5

8.5

19.2

27.8

50.9

22.3

10

19.7

30.3

48.4

23.7

 Diabetes

%

0.0

11.1

8.3

0.0

5.0

1.4

1.9

1.9

5.7

2.3

1.3

3.3

3.0

4.7

2.7

 Nephrolithiasis

%

0.0

0.0

8.3

0.0

2.5

4.2

11.5

5.6

3.8

5.4

3.8

9.8

6.1

3.1

5.0

Women

N

10

16

9

6

41

108

119

96

47

370

118

135

105

53

411

Age (yrs)

M (SD)

46.3 (2.7)

54.9 (2.6)

64.2 (2.8)

77.2 (5.4)

58.1 (10.5)

44.6 (3.0)

54.2 (3.0)

64.1 (3.1)

74.8 (4.6)

53.1 (12.7)

44.7(3.0)

54.3 (2.9)

64.1 (3.1)

75.1 (4.7)

53.5 (12.6)

Urinary Cd (μg/g Creat)

GM (GSD)

0.8 (2.3)

1.3 (2.0)

1.0 (3.2)

1.3 (1.8)

1.1 (2.3)

6.5 (2.1)

7.6 (1.9)

7.5 (2.0)

6.5 (1.8)

7.0 (1.9)

5.4 (2.6)

6.1 (2.3)

6.3 (2.5)

5.4 (2.2)

5.9 (2.3)

Blood cadmium (μg/L)

GM (GSD)

0.5 (1.7)

1.0 (2.1)

0.9 (2.1)

1.1 (1.9)

0.8 (2.1)

4.5 (2.2)

5.7 (1.9)

5.7 (2.0)

5.1 (1.8)

5.2 (2.0)

3.7 (2.7)

4.6 (2.4)

4.9 (2.4)

4.3 (2.2)

4.4 (2.5)

ß2-MG (μg/g Creat)

GM (GSD)

43.9 (2.2)

160 (4.2)

260 (6.4)

1952 (8.9)

187.2 (6.6)

151.9 (6.5)

154 (4.7)

311 (8.1)

397 (7.6)

207.7 (6.6)

137 (6.3)

155 (4.6)

307 (7.9)

475 (8.0)

205.6 (6.6)

NAG (IU/g Creat)

GM (GSD)

2.7 (1.7)

5.3 (2.3)

4.6 (2.1)

10.7 (2.0)

4.8 (2.3)

4.9 (1.7)

5.6 (1.7)

6.6 (1.8)

8.6 (1.8)

5.7 (1.9)

4.6 (1.8)

5.6 (1.8)

6.4 (1.9)

8.8 (1.8)

5.6 (1.9)

Smoking habit

                

 Ex-smokers

%

0.0

6.3

44.4

83.3

24.4

11.1

27.7

53.1

42.6

26.4

10.2

25.2

52.4

47.2

26.2

 Smokers

%

0.0

25.0

11.1

0.0

0.1

21.3

29.6

28.1

42.6

23.2

19.5

26.7

26.7

37.7

22.2

Prevalence of illness

                

 Hypertension

%

30

25

22.2

50

29.3

15.7

30.3

40.6

55.3

26.8

16.9

29.6

39

54.7

29.5

 Diabetes

%

0.0

25.0

22.2

16.7

17.1

5.6

5.9

11.5

4.3

5.9

5.1

8.1

12.4

5.7

6.9

 Nephrolithiasis

%

0.0

0.0

0.0

0.0

0.0

0.0

10.9

4.2

12.8

5.2

0.0

9.6

3.8

11.3

4.8

  1. SD: standard deviation. GM: geometric mean. GSD: geometric standard deviation.
  2. The levels of urinary and blood Cd were significantly greater in the polluted area than those in the non-polluted area for all age groups (P < 0.001 student’s t-test).