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Table 1 Subject characteristics for ART-naïve and ART groups

From: Quality of life in individuals living with HIV/AIDS attending a public sector antiretroviral service in Cape Town, South Africa

  Total ART-naïve ART P value
  (n = 903) (n = 435) (n = 468)  
  N (%) N (%) N (%)  
Age, yrs, median (IQR) 33 (29–40) 32 (28–38) 35 (30–42) < 0.0001
Female 697 (77.2) 331 (76.1) 366 (78.2) 0.450
Education     
No education 58 (6.4) 25 (5.8) 33 (7.1) 0.654
≤ Grade 12 820 (90.8) 399 (91.7) 421 (90.0)  
>Grade 12 25 (2.8) 11 (2.5) 14 (3.0)  
Housing density (persons/room), median (IQR) 2 (1–3) 2 (1–3) 1.5 (1–3) 0.002
Employment     
Full or part time 250 (27.7) 115 (26.4) 135 (28.9) 0.791
Unemployed 648 (71.8) 317 (72.9) 331 (70.3)  
Other 5 (0.6) 3 (0.7) 2 (0.4)  
Current smoker 136 (15.1) 75 (17.2) 61(13.0) 0.077
Ever drank alcohol 426 (47.2) 226 (52.0) 200 (42.8) 0.006
CD4 count, cells/μl median (IQR) 289 (184–455) 224 (153–437) 318 (222–468) <0.0001
Previous TB 379 (49.8) 254 (64.0) 125 (34.3) < 0.001
Treatment regimens     
d4T 3TC EFV - - 238 (51.8)  
d4T 3TC NVP - - 169 (36.3)  
AZT 3TC EFV - - 11 (2.4)  
AZT 3TC NVP - - 45 (9.6)  
Other - - 2 (0.4)  
Duration of treatment (months)     
d4T - - 13.0 (8.0-20.0)  
AZT - - 12.0 (7.0-18.5)  
Body composition     
BMI, kg/m2, median (IQR) 25.2 (22.0 -29.6) 24.2 (21.4-29.0) 26.0 (22.9-30.0) 0.0004
Waist-to-hip ratio, mean ± SD 0.85 ± 0.07 0.84 ± 0.07 0.87 ± 0.08 < 0.01
Sagittal height, cm, median (IQR) 19.3 (17.0-22.0) 18.3 (16.5-21.0) 19.8 (17.5-22.5) <0.0001
Sum of skinfolds, median (IQR) 108.8 (69.5-158.7) 103.8 (64.4-164.1) 111.5 (74.1-153.8) 0.557
Calf skinfolds, median (IQR) 14.6 (8.4 – 21.6) 15.6 (9.3-22.6) 13.4 (7.8-20.5) 0.012
  1. d4T, Stavudine; AZT,.Zidovudine; 3TC, Lamuvidine; EFV, Efavirenz; NVP, Nevirapine.