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Table 3 Distribution of reported or observed pigmentation characteristics and 25(OH)D levels by pigmentation genetic scores

From: Skin pigmentation, sun exposure and vitamin D levels in children of the Avon Longitudinal Study of Parents and Children

 

Mean ± SD of pigmentation score

 

Mean ± SD

 
 

Skin colour score

Tanning score

Freckling score

Na

25(OH)D (nmol/l)

Nb

Skin colour change

      

Always burns never tans

6.29 ± 1.25

12.16 ± 1.97

7.16 ± 1.54

47

62.8 ± 14.6

45

Burns easily rarely tans

5.69 ± 1.27

11.76 ± 2.19

6.82 ± 1.81

547

63.4 ± 16.7

518

Doesn’t change

5.41 ± 1.18

11.19 ± 2.02

6.41 ± 1.66

235

64.9 ± 18.4

225

Tans easily rarely burns

4.89 ± 1.17

10.35 ± 2.00

5.85 ± 1.61

2209

63.2 ± 19.9

2098

Always tans never burns

4.57 ± 1.11

9.92 ± 1.95

5.56 ± 1.54

924

63.6 ± 20.1

875

p-value

<0.0001

<0.0001

<0.0001

3962

0.81/0.53c

3761

Child badly burnt

      

No

5.00 ± 1.21

10.54 ± 2.08

5.96 ± 1.68

3501

62.4 ± 18.7

3465

Yes

5.40 ± 1.29

11.27 ± 2.17

6.42 ± 1.70

613

63.7 ± 19.3

594

p-value

1.5×10-13

2.2×10-15

6.4×10-10

4114

0.13/0.17c

4059

Any freckles

      

No

4.70 ± 1.14

10.06 ± 1.96

5.52 ± 1.57

432

60.8 ± 19.1

391

Yes

5.45 ± 1.23

11.41 ± 2.18

6.79 ± 1.80

297

63.7 ± 19.2

270

p-value

2.0×10-16

2.1×10-17

2.3×10-22

729

0.05/0.04c

661

Mole count

      

49 months

      

Q1 (0–6)

4.84 ± 1.17

10.27 ± 1.90

5.80 ± 1.60

227

61.3 ± 16.6

193

Q2 (7–9)

4.94 ± 1.18

10.30 ± 2.04

5.66 ± 1.64

144

60.2 ± 15.4

123

Q3 (10–14)

5.03 ± 1.25

10.75 ± 2.22

6.08 ± 1.95

186

61.5 ± 25.2

166

Q4 (15–57)

5.37 ± 1.22

11.24 ± 2.27

6.49 ± 1.80

176

62.8 ± 16.7

169

p-value

0.0002

1.89×10-6

3.16×10-5

733

0.71/0.74c

651

61 months

      

Q1 (0–10)

4.83 ± 1.22

10.07 ± 2.06

5.55 ± 1.75

191

60.4 ± 17.6

164

Q2 (11–16)

4.84 ± 1.24

10.43 ± 2.11

5.90 ± 1.67

174

60.5 ± 21.7

162

Q3 (17–25)

5.05 ± 1.17

10.68 ± 2.16

6.23 ± 1.82

180

61.4 ± 15.1

163

Q4 (26–86)

5.30 ± 1.25

11.21 ± 2.10

6.43 ± 1.73

166

65.2 ± 21.5

160

p-value

0.001

3.50×10-7

4.26×10-7

711

0.08/0.09c

649

186 months

      

Q1 (0–2)

5.05 ± 1.22

10.56 ± 2.15

6.05 ± 1.76

688

60.6 ± 17.0

704

Q2 (3–9)

4.92 ± 1.20

10.50 ± 2.14

6.03 ± 1.72

691

61.4 ± 19.1

717

Q3 (10–22)

5.00 ± 1.21

10.60 ± 2.08

6.01 ± 1.67

710

62.3 ± 18.5

729

Q4 (23–153)

5.21 ± 1.18

10.83 ± 2.04

6.03 ± 1.65

665

63.5 ± 18.5

656

p-value

0.0001

0.02

0.99

2754

0.02/0.01c

2806

  1. aN = number of individuals included in the analysis of pigmentation scores.
  2. bN = number of individuals included in the analysis of 25(OH)D levels.
  3. cAdjusted for sex and age at blood draw.