The association between maternal hepatitis B e antigen status, as a proxy for perinatal transmission, and the risk of hepatitis B e antigenaemia in Gambian children

Table 2 Risk factors for HBeAg positivity in HBsAg-positive index women (2 ^nd generation)

Variables	HBsAg (+) HBeAg (+) index women (n = 38)		HBsAg (+) HBeAg (−) index women (n = 38)		Crude odds ratios			Adjusted odds ratios¹
	No	%	No	%	OR	95% CI	P	OR	95% CI	P
Maternal HBsAg (1^st generation)
Negative	20	83.3	24	92.3	1.0		0.3	1.0		0.9
Positive	4	16.7	2	7.7	2.4	0.4-14.5		1.2	0.1-23.2
Maternal HBeAg (1^st generation)
Negative	24	100	26	100	1.0			1.0
Positive	0	0	0	0	N/A			N/A
No. of older siblings with positive HBsAg
0	22	84.6	24	82.8	1.0		0.9	1.0		0.9
1-2	4	15.4	5	17.2	0.9	0.2-3.7		0.9	0.2-5.5
No. of older siblings with positive HBeAg
0	25	96.2	29	100	1.0			1.0
1	1	3.8	0	0	N/A			N/A

¹Model included maternal HBsAg, number of older siblings with HBsAg, year of birth, and total sibship size.

ISSN: 1471-2458