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Table 3 Likelihood of symptom persistence (symptoms at 25 weeks after treatment initiation): logistic regression results

From: Tuberculosis treatment discontinuation and symptom persistence: an observational study of Bihar, India’s public care system covering >100,000,000 inhabitants

  Univariate regression Multivariate regression
  All patients All patients Patients with prior TB Patients with no prior TB
  OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI)
Prior TB status
Prior TB treatment episode 4.59* (2.17 - 9.70) 5.05* (1.90 - 13.38)     
Prior TB & completed prior treatment 1.63 (0.58 - 4.62) 2.40 (0.78 - 7.37) 0.81 (0.26 - 2.48)   
Current illness treatment and illness characteristics
Total weeks from symptom onset to treatment initiation 1.01 (0.97 - 1.05) 0.96 (0.91 - 1.01) 0.95 (0.86 - 1.05) 0.96 (0.89 - 1.02)
Number of providers visited 2.73* (1.42 - 5.25) 2.06 (0.93 - 4.56) 3.76* (1.00 - 14.11) 1.10 (0.25 - 4.86)
Treatment or medication fees 2.79* (1.16 - 6.71) 1.17 (0.42 - 3.25) 1.30 (0.12 - 14.46) 1.59 (0.43 - 5.92)
Travel costs 2.16* (1.10 - 4.27) 1.89 (0.91 - 3.92) 0.73 (0.06 - 8.66) 1.74 (0.81 - 3.70)
Treatment, medication and travel costs 0.13* (0.05 - 0.33) 0.16* (0.06 - 0.46) 1.30 (0.08 - 22.00) 0.10* (0.03 - 0.39)
Remained in care 0-8 weeks 1.59 (0.73 - 3.43) 0.50 (0.19 - 1.35) 0.35 (0.08 - 1.55) 0.70 (0.17 - 2.89)
Remained in care 9-16 weeks 0.90 (0.31 - 2.61) 0.90 (0.29 - 2.76) 0.29 (0.07 - 1.17) 2.12 (0.75 - 6.02)
2 or Fewer symptoms at treatment initiation** 0.95 (0.57 - 1.58) 1.10 (0.64 - 1.89) 0.89 (0.28 - 2.84) 1.93 (0.96 - 3.88)
3-4 symptoms at treatment initiation** 0.57 (0.28 - 1.16) 0.50 (0.18 - 1.43) 0.42 (0.12 - 1.45) 1.11 (0.37 - 3.35)
Patient and household characteristics
Male 0.66* (0.45 - 0.96) 0.56* (0.33 - 0.93) 0.41 (0.15 - 1.12) 0.76 (0.45 - 1.30)
Age 0.97 (0.92 - 1.01) 0.97 (0.91 - 1.03) 0.97 (0.88 - 1.07) 0.96 (0.90 - 1.03)
Age squared 1.00* (1.00 - 1.00) 1.00 (1.00 - 1.00) 1.00 (1.00 - 1.00) 1.00 (1.00 - 1.00)
Education 0.95 (0.91 - 1.00) 1.02 (0.95 - 1.09) 0.99 (0.87 - 1.13) 0.99 (0.92 - 1.06)
Hindu 0.65 (0.41 - 1.03) 0.54 (0.27 - 1.08) 0.61 (0.10 - 3.94) 0.49 (0.22 - 1.08)
Scheduled Caste, Tribe, other backwards class 0.85 (0.52 - 1.38) 0.90 (0.51 - 1.59) 0.71 (0.09 - 5.56) 0.92 (0.46 - 1.86)
Number of Kids 1.02 (0.88 - 1.19) 1.03 (0.84 - 1.28) 0.78 (0.54 - 1.12) 1.14 (0.88 - 1.49)
Household size 1.06 (0.96 - 1.17) 0.99 (0.87 - 1.13) 1.18 (0.89 - 1.57) 0.90 (0.77 - 1.06)
Poor 2.37* (1.44 - 3.91) 2.94* (1.51 - 5.72) 1.89 (0.66 - 5.38) 2.91* (1.49 - 5.68)
Middle income 0.86 (0.45 - 1.63) 1.02 (0.52 - 2.00) 0.81 (0.24 - 2.73) 0.84 (0.48 - 1.47)
Observations 1007 1007 196 811
  1. *p < 0.05.
  2. **Comparator group is ≥5 Symptoms at Treatment Initiation.