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Table 3 Likelihood of symptom persistence (symptoms at 25 weeks after treatment initiation): logistic regression results

From: Tuberculosis treatment discontinuation and symptom persistence: an observational study of Bihar, India’s public care system covering >100,000,000 inhabitants

 

Univariate regression

Multivariate regression

 

All patients

All patients

Patients with prior TB

Patients with no prior TB

 

OR

(95% CI)

OR

(95% CI)

OR

(95% CI)

OR

(95% CI)

Prior TB status

Prior TB treatment episode

4.59*

(2.17 - 9.70)

5.05*

(1.90 - 13.38)

    

Prior TB & completed prior treatment

1.63

(0.58 - 4.62)

2.40

(0.78 - 7.37)

0.81

(0.26 - 2.48)

  

Current illness treatment and illness characteristics

Total weeks from symptom onset to treatment initiation

1.01

(0.97 - 1.05)

0.96

(0.91 - 1.01)

0.95

(0.86 - 1.05)

0.96

(0.89 - 1.02)

Number of providers visited

2.73*

(1.42 - 5.25)

2.06

(0.93 - 4.56)

3.76*

(1.00 - 14.11)

1.10

(0.25 - 4.86)

Treatment or medication fees

2.79*

(1.16 - 6.71)

1.17

(0.42 - 3.25)

1.30

(0.12 - 14.46)

1.59

(0.43 - 5.92)

Travel costs

2.16*

(1.10 - 4.27)

1.89

(0.91 - 3.92)

0.73

(0.06 - 8.66)

1.74

(0.81 - 3.70)

Treatment, medication and travel costs

0.13*

(0.05 - 0.33)

0.16*

(0.06 - 0.46)

1.30

(0.08 - 22.00)

0.10*

(0.03 - 0.39)

Remained in care 0-8 weeks

1.59

(0.73 - 3.43)

0.50

(0.19 - 1.35)

0.35

(0.08 - 1.55)

0.70

(0.17 - 2.89)

Remained in care 9-16 weeks

0.90

(0.31 - 2.61)

0.90

(0.29 - 2.76)

0.29

(0.07 - 1.17)

2.12

(0.75 - 6.02)

2 or Fewer symptoms at treatment initiation**

0.95

(0.57 - 1.58)

1.10

(0.64 - 1.89)

0.89

(0.28 - 2.84)

1.93

(0.96 - 3.88)

3-4 symptoms at treatment initiation**

0.57

(0.28 - 1.16)

0.50

(0.18 - 1.43)

0.42

(0.12 - 1.45)

1.11

(0.37 - 3.35)

Patient and household characteristics

Male

0.66*

(0.45 - 0.96)

0.56*

(0.33 - 0.93)

0.41

(0.15 - 1.12)

0.76

(0.45 - 1.30)

Age

0.97

(0.92 - 1.01)

0.97

(0.91 - 1.03)

0.97

(0.88 - 1.07)

0.96

(0.90 - 1.03)

Age squared

1.00*

(1.00 - 1.00)

1.00

(1.00 - 1.00)

1.00

(1.00 - 1.00)

1.00

(1.00 - 1.00)

Education

0.95

(0.91 - 1.00)

1.02

(0.95 - 1.09)

0.99

(0.87 - 1.13)

0.99

(0.92 - 1.06)

Hindu

0.65

(0.41 - 1.03)

0.54

(0.27 - 1.08)

0.61

(0.10 - 3.94)

0.49

(0.22 - 1.08)

Scheduled Caste, Tribe, other backwards class

0.85

(0.52 - 1.38)

0.90

(0.51 - 1.59)

0.71

(0.09 - 5.56)

0.92

(0.46 - 1.86)

Number of Kids

1.02

(0.88 - 1.19)

1.03

(0.84 - 1.28)

0.78

(0.54 - 1.12)

1.14

(0.88 - 1.49)

Household size

1.06

(0.96 - 1.17)

0.99

(0.87 - 1.13)

1.18

(0.89 - 1.57)

0.90

(0.77 - 1.06)

Poor

2.37*

(1.44 - 3.91)

2.94*

(1.51 - 5.72)

1.89

(0.66 - 5.38)

2.91*

(1.49 - 5.68)

Middle income

0.86

(0.45 - 1.63)

1.02

(0.52 - 2.00)

0.81

(0.24 - 2.73)

0.84

(0.48 - 1.47)

Observations

1007

1007

196

811

  1. *p < 0.05.
  2. **Comparator group is ≥5 Symptoms at Treatment Initiation.