Table 1 Target compounds to be analyzed in bio-specimens
From: Rationale and study design of the Japan environment and children’s study (JECS)
Group | Target compounds |
|---|---|
Metals | Lead, cadmium, total mercury, methyl mercury, arsenics and its compounds including, arsenobetaine, metylarsonic acid, dimethylarsinic acid, trimethylarsine oxide, etc. |
Inorganic substances | Iodine, perchlorate, nitrate nitrogen, etc |
Chlorinated POPs (Persistent organic pollutants) | Polychlorinated biphenysl (PCBs), hydroxylated polychlorinated biphenyl (OH-PCB), dioxins (PCDDs, PCDFs, Co-PCBs), pexachlorobenzene (HCB), pentachlorobennzene (PeCB), etc. |
Pesticides (including pesticide-POPs) | Chlordanes, DDT and its metabolites (DDE, etc.), drin compounds for agriculture (dieldrin, etc.), heptachlor, hexachlorocyclohexaxne (HCH), mirex, chlordecone, toxaphene, organophophorus pesticide metabolites (DMP, DEP, DMTP, DETP, etc.), fenitrothion metabolite (methylnitrophenol), acephate metabolite (methamidophos), pyrethroid metabolites (PBA, DCCA, etc.), dithiocarbamate fungicide metabolites (ethylene thiourea, etc.), neonicotinoid metabolites, pentachlorophenol (PCP), atrazine, dymron, glyphosate, flutolanil, iprodione, flusulfamide, etc. |
Brominated POPs | Polybromodiphenylethers (PBDEs), polybromobiphenyls (PBBs), hexabromocyclododecan (HBCD), etc. |
Organofluorine compounds | Perfluorooctanoic acid (PFOA), perfluorooctane sulfonate (PFOS), perfluorononanoic acid (PFNA), etc. |
Aroma compounds | Nitromusks, cyclic musks, etc. |
Phthalate metabolites | Mono (2-ethylhexyl) phthalates, etc. |
Phenols | Bisphenol A, Nonyphenols, Parabens, etc. |
Others | Triclosan, benzophenone, N, N-diethyl-meta-toluamide (DEET), polyaromatic hydrocarbons (PAHs) and their metabolites (1-hydroxypyrene, 3-hydroxyphenanthrebe, etc.), cotinine, thiocyanate, dichlorobenzene, phytoestrogen, caffeine, pyridine, acrylamide, tributyl phosphate, tributoxyethl phosphate, 8-hydroxydeoxyguanosine (8-OHdG), etc. |