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Table 1 Target compounds to be analyzed in bio-specimens

From: Rationale and study design of the Japan environment and children’s study (JECS)

Group Target compounds
Metals Lead, cadmium, total mercury, methyl mercury, arsenics and its compounds including, arsenobetaine, metylarsonic acid, dimethylarsinic acid, trimethylarsine oxide, etc.
Inorganic substances Iodine, perchlorate, nitrate nitrogen, etc
Chlorinated POPs (Persistent organic pollutants) Polychlorinated biphenysl (PCBs), hydroxylated polychlorinated biphenyl (OH-PCB), dioxins (PCDDs, PCDFs, Co-PCBs), pexachlorobenzene (HCB), pentachlorobennzene (PeCB), etc.
Pesticides (including pesticide-POPs) Chlordanes, DDT and its metabolites (DDE, etc.), drin compounds for agriculture (dieldrin, etc.), heptachlor, hexachlorocyclohexaxne (HCH), mirex, chlordecone, toxaphene, organophophorus pesticide metabolites (DMP, DEP, DMTP, DETP, etc.), fenitrothion metabolite (methylnitrophenol), acephate metabolite (methamidophos), pyrethroid metabolites (PBA, DCCA, etc.), dithiocarbamate fungicide metabolites (ethylene thiourea, etc.), neonicotinoid metabolites, pentachlorophenol (PCP), atrazine, dymron, glyphosate, flutolanil, iprodione, flusulfamide, etc.
Brominated POPs Polybromodiphenylethers (PBDEs), polybromobiphenyls (PBBs), hexabromocyclododecan (HBCD), etc.
Organofluorine compounds Perfluorooctanoic acid (PFOA), perfluorooctane sulfonate (PFOS), perfluorononanoic acid (PFNA), etc.
Aroma compounds Nitromusks, cyclic musks, etc.
Phthalate metabolites Mono (2-ethylhexyl) phthalates, etc.
Phenols Bisphenol A, Nonyphenols, Parabens, etc.
Others Triclosan, benzophenone, N, N-diethyl-meta-toluamide (DEET), polyaromatic hydrocarbons (PAHs) and their metabolites (1-hydroxypyrene, 3-hydroxyphenanthrebe, etc.), cotinine, thiocyanate, dichlorobenzene, phytoestrogen, caffeine, pyridine, acrylamide, tributyl phosphate, tributoxyethl phosphate, 8-hydroxydeoxyguanosine (8-OHdG), etc.