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Table 4 Results; Cross Sectional Studies

From: Beyond BMI: The “Metabolically healthy obese” phenotype & its association with clinical/subclinical cardiovascular disease and all-cause mortality -- a systematic review

Study Subjects (Age, Male) Outcome Results
Marini [25] N = 153 CCA-IMT Mean CCA-IMT: MHO = 0.79 (0.08) vs. MHNW = 0.61 (0.11) p < 0.001
MHO = NR (35, 0%)
MHNW = 73 (34, 0%)
Stefan [26] N = 314 CCA-IMT Mean CCA-IMT: MHO = 0.54 (0.02) vs. MHNW = 0.51 (0.02) p = NS
MHO = 31 (47, 39%)
MHNW = 54 (45, 17%)
Irace [29] N = 1842 (30–80 years old, 55%) MHO = NR CCA-IMT Mean CCA-IMT: MHO = NR vs. MHNW = NR
MHNW = NR   • AdjustedA OR of CCA-IMT MetS: 1.42 (1.10-1.83) p = 0.01BMI: p = NS
Khan [27] N = 475 CCA-IMT Mean CCA- IMT: MHO = 0.68 (0.09) vs. MHNW =0.64 (0.08) p < 0.001
MHO = 260 (51, 0%) aPWV Mean aPWV: MHO = 809.9 (182.3) vs. MHNW =731 (176.4) p < 0.001
MHNW = 145 (51, 0%) CAC Frequency (%) with increased CAC: MHO = 53 (20%) vs. MHNW =13 (9%) p < 0.001
  AC Frequency (%) with increased AC: MHO = 130 (50%) vs. MHNW =47 (32%) p < 0.001
   •AdjustedB OR's of CAC and AC associated with MHO vs. MHNW CAC: 2.38 (1.20,4.70) p = 0.01; AC: 2.37 (1.49.3.80) p < 0.001
   •AdjustedB regression coefficients associated with MHO vs. MHNW CCA-IMT: 0.034 p < 0.001; aPWV: 59.7 p = 0.001
Park [28] N = 2540 MHO = 71 (52, 45%) CCA-IMT Mean CCA IMT: MHO = 0.72 (0.06) vs. MHNW = 0.70 (0.06) p = NS
MHNW = 286 (52, 52%) aPWV Mean aPWV: MHO = 12.8 (1.1) vs. MHNW = 12.9 (1.6) p = NS
  LVMI Mean LVMI: MHO = 42.4 (7.4) vs. MHNW = 35.4 (6.6) p < 0.01
  E/A ratio Mean E/A ratio: MHO = 1.17 (0.34) vs. MHNW = 1.34 (0.41) p < 0.05
  1. AAdjusted for age, sex, smoking, metabolic syndrome, BMI, LDL; BAdjusted for age, site of recruitment, education, race, smoking; CAdjusted for age, sex, heart rate, CRP, medication for hypertension, treatment for diabetes mellitus.