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Table 5 Association between Phe levels (in the previous 12 months and at assessment) and QoL scores in mild PKU patients on BH 4 treatment and classical patients on diet expressed as regression coefficients (RC) with 95% confidence intervals (95%CI) and p values

From: Quality of Life (QoL) assessment in a cohort of patients with Phenylketonuria

Mild PKU patients on BH4
  RC 95% CI p value
phenylalanine in previous 12 months - 0.13 (-0.21; -0.05) < 0.01
phenylalanine at assessment - 0,11 (-0.18; -0.04) < 0.01
Classical PKU patients on diet
  RC 95% CI p value
phenylalanine in previous 12 months - 0.08 (-0.12; -0.04) < 0.01
phenylalanine at assessment - 0.08 (-0.11; -0.04) < 0.01