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Table 3 Independent predictors of virological and immunological failure

From: Pharmacy refill adherence outperforms self-reported methods in predicting HIV therapy outcome in resource-limited settings

 

> 400 copies/ml

>1,000 copies/ml

Immunological failure

Predictor

AOR (95% CI)

p-value

AOR (95% CI)

p-value

AOR (95% CI)

p-value

Pharmacy refill adherence

0.45 (0.21 - 0.92)

0.03

0.24 (0.09 - 0.59)

<0.01

0.19 (0.04 - 0.81)

0.02

Being on triomune regimen

2.39 (1.16 - 5.07)

0.02

3.32 (1.36 - 8.64)

0.01

2.09 (0.66 - 7.07)

0.22

Having baseline CD4 T lymphocytes count < 200 cell/μl

1.59 (0.65 - 3.93)

0.31

3.91 (1.38 - 11.59)

0.01

2.05 (0.58 - 7.01)

0.25

Having baseline undetectable viral load

0.33 (0.12 - 0.87)

0.03

0.23 (0.07 - 0.7)

0.01

0.37 (0.1 - 1.35)

0.13

Being able to remember diagnosis date

0.36 (0.17 - 0.75)

0.01

0.23 (0.09 - 0.57)

<0.01

0.27 (0.07 - 0.84)

0.03

Age per 1 year older

1.01 (0.97 - 1.05)

0.71

1 (0.95 - 1.05)

0.94

0.97 (0.89 - 1.04)

0.37

Weight per 1 kg higher

1.05 (1.01 - 1.08)

0.01

1.05 (1.01 - 1.1)

0.01

0.99 (0.94 - 1.04)

0.65

  1. Key: AOR (CI) = Adjusted odds ratio (confidence interval).