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Table 1 Parameter values

From: A large-scale immuno-epidemiological simulation of influenza A epidemics

 

V 0

β

p

c

δ

k

θ

a

Description

Inoculum

Infection

Viral

Viral

Infected

Latent

Rate of

Symptoms

 

size

rate

production

clearance

cell decay

cell

symptoms

clearance

   

rate

rate

rate

rate

onset

rate

Units

TCID 50 mL

(TCID 50 - 1 mL day -1)

TCID 50 - 1 mL day -1

(day -1)

(day -1)

(day -1)

day -1[S]-1

(day -1)

Baseline (α 0)

0.02

0.083

4000

3

1.3

5

2.5

0.55

Lower Bounds

0.75e-5

β 0/35

p 0/35

8

0.5

2

θ 0/35

a 0/35

Upper Bounds

1

35 β 0

88 p 0

40

2

6

35 θ 0

35 a 0

Best fit

7.50e-6

0.0674

40356

8.00

1.364

3.684

2.75

0.498

  1. The reported bounds are used for parameter estimation. Epithelial cells are scaled and hence have non-dimensional units. Symptoms are based on a symptoms score value, which unit we denote by [S].