Table 2 Hazard ratios for cancer mortality by body mass index and cardiorespiratory fitness among never-smokers and current smokers
From: Cardiorespiratory fitness, body mass index, and cancer mortality: a cohort study of Japanese men
Variable | N | Man-years | No. of cancer deaths | Age adjusted hazard ratio | Multivariable hazard ratio |
|---|---|---|---|---|---|
(95% CI) | (95% CI) | ||||
Never-smokers (n = 2,152) | |||||
BMI | |||||
1st tertile (18.5-21.5 kg · m-2) | 716 | 14,550 | 11 | 0.93 (0.39 - 2.18) | 0.96 (0.41 - 2.27) |
2nd tertile (21.6-23.6 kg · m-2) | 725 | 14,681 | 10 | 1.00 (Reference) | 1.00 (Reference)a |
3rd tertile (23.7-37.4 kg · m-2) | 711 | 14,483 | 13 | 1.07 (0.47 - 2.44) | 1.23 (0.51 - 2.23) |
P for trend | 0.727 | 0.576 | |||
Cardiorespiratory fitness | |||||
1st tertile (Lowest) | 704 | 14,253 | 13 | 1.00 (Reference) | 1.00 (Reference)b |
2nd tertile | 760 | 15,555 | 9 | 0.68 (0.29 - 1.58) | 0.67 (0.28 - 1.60) |
3rd tertile (Highest) | 688 | 13,905 | 12 | 1.02 (0.46 - 2.23) | 0.99 (0.43 - 2.28) |
P for trend | 0.990 | 0.986 | |||
Current smokers (n = 5,552) | |||||
BMI | |||||
1st tertile (18.5-21.5 kg · m-2) | 1,766 | 35,646 | 36 | 0.79 (0.52 - 1.22) | 0.73 (0.47 - 1.13) |
2nd tertile (21.6-23.6 kg · m-2) | 1,903 | 38,110 | 49 | 1.00 (Reference) | 1.00 (Reference)a |
3rd tertile (23.7-37.4 kg · m-2) | 1,883 | 37,902 | 44 | 0.84 (0.56 - 1.26) | 0.72 (0.47 - 1.10) |
P for trend | 0.856 | 0.923 | |||
Cardiorespiratory fitness | |||||
1st tertile (Lowest) | 1,794 | 35,798 | 51 | 1.00 (Reference) | 1.00 (Reference)b |
2nd tertile | 1,960 | 39,610 | 50 | 0.88 (0.60 - 1.30) | 0.82 (0.55 - 1.23) |
3rd tertile (Highest) | 1,798 | 36,250 | 28 | 0.60 (0.38 - 0.95) | 0.55 (0.34 - 0.89) |
P for trend | 0.032 | 0.015 |