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Table 1 Characteristics of the included studies

From: Emollient therapy for preterm newborn infants – evidence from the developing world

Author

Country

Target population

Emollient

Dose and frequency

Follow up

Arora 2005 [14]

India

Neonates <37 weeks and <1500 g

Sunflower oil

4 times a day (10ml/kg/day)

28 days

Darmstadt 2004 [20]

Egypt

Neonates <34 weeks and <72hr old. Gestational age was determined with an average of gestational age values by last menstrual period, per the criteria of Ballard and Dubowitz

Sunflower oil

3 times a day for 14 days and then 2 times a day (12g/kg/day)

28 days

Darmstadt 2005 [11]

Bangladesh

Neonates <33 weeks and <72hr old. Gestational age was identified by doctors, according to the methods described by Dubowitz and Ballard, and on the basis of maternal dates (time from the first day of the last menstrual period); the average of the three measures was used

A. Sunflower seed oil

B. Aquaphor

3 times a day for 14 days and then 2 times a day (12g/kg/day)

28 days or until discharge if <28 days

Darmstadt 2008 [21]

Bangladesh

Neonates <33 weeks and <72hr old. Gestational age was identified by doctors, according to the methods described by Dubowitz and Ballard, and on the basis of maternal dates (time from the first day of the last menstrual period); the average of the three measures was used

A. Sunflower seed oil

B. Aquaphor

3 times a day for 14 days and then 2 times a day (12g/kg/day)

28 days or until discharge if <28 days

Kumar 2012 [24]

India

Neonates <35 weeks and <1800 g

Sunflower oil

10ml/kg/day

28 days

Salam (Unpublished) [25]

Pakistan

Neonates ≥26 weeks and ≤37 weeks with a birth weight >750g. Gestational age estimated from ultrasound records and Ballard scores at admission

Coconut oil

2 times a day (10 ml/kg/day)

28 days

Sankaranarayanan 2005 [22]

India

Preterm (1500 to 2000g) and term (>2500g)

A. Coconut oil

B. Mineral oil

4 times a day

31 days

Soriano 2000 [23]

Brazil

Neonates 28-34 weeks and <1700 g

Soybean oil

3 times a day (12g/kg/day)

30 days