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Table 3 Quality assessment of studies of community case management for the treatment of diarrhea

From: Effect of community based interventions on childhood diarrhea and pneumonia: uptake of treatment modalities and impact on mortality

  Quality Assessment Summary of Findings
  Directness No of events  
No of studies Design Limitations Consistency Generalizability to population of interest Generalizability to intervention of interest Intervention Control Relative Risk (95% CI)
Diarrhea Specific mortality 0–1 years: low outcome specific quality of evidence
One Before/ After No major limitation   Asia Only WHO case management by local health workers 0 11 0.05 [0.00, 0.87]
Diarrhea Specific mortality 1-4 years: low outcome specific quality of evidence
One Before/ After No major limitation   Asia Only WHO case management by local health workers 3 1 2.98 [0.31, 28.63]
Diarrhea Specific mortality 0-4 years: moderate outcome specific quality of evidence
One Concurrent No major limitation   Asia Only WHO case management by local health workers 3 8 0.56 [0.15, 2.11]
Two Before/After No major limitation Both studies show benefit Asia Only WHO case management by local health workers 6 19 0.32 [0.13, 0.80]
Two Concurrent: Before/After No major limitation Both studies show benefit Asia Only WHO case management by local health workers 6 20 0.37 [0.15, 0.93]
All-cause mortality 0–4 years: moderate outcome specific quality of evidence
One Concurrent No major limitation   Asia Only WHO case management by local health workers 157 221 1.06 [0.86, 1.30]
Two Before/After No major limitation One shows benefit Asia Only WHO case management by local health workers 194 208 0.80 [0.47, 1.35]
Two Concurrent; Before/After No major limitation One shows benefit Asia Only WHO case management by local health workers 194 285 0.94 [0.78, 1.12]