Table 3 Quality assessment of studies of community case management for the treatment of diarrhea
| Â | Quality Assessment | Summary of Findings | ||||||
|---|---|---|---|---|---|---|---|---|
| Â | Directness | No of events | Â | |||||
No of studies | Design | Limitations | Consistency | Generalizability to population of interest | Generalizability to intervention of interest | Intervention | Control | Relative Risk (95% CI) |
Diarrhea Specific mortality 0–1 years: low outcome specific quality of evidence | ||||||||
One | Before/ After | No major limitation | Â | Asia Only | WHO case management by local health workers | 0 | 11 | 0.05 [0.00, 0.87] |
Diarrhea Specific mortality 1-4 years: low outcome specific quality of evidence | ||||||||
One | Before/ After | No major limitation | Â | Asia Only | WHO case management by local health workers | 3 | 1 | 2.98 [0.31, 28.63] |
Diarrhea Specific mortality 0-4 years: moderate outcome specific quality of evidence | ||||||||
One | Concurrent | No major limitation | Â | Asia Only | WHO case management by local health workers | 3 | 8 | 0.56 [0.15, 2.11] |
Two | Before/After | No major limitation | Both studies show benefit | Asia Only | WHO case management by local health workers | 6 | 19 | 0.32 [0.13, 0.80] |
Two | Concurrent: Before/After | No major limitation | Both studies show benefit | Asia Only | WHO case management by local health workers | 6 | 20 | 0.37 [0.15, 0.93] |
All-cause mortality 0–4 years: moderate outcome specific quality of evidence | ||||||||
One | Concurrent | No major limitation | Â | Asia Only | WHO case management by local health workers | 157 | 221 | 1.06 [0.86, 1.30] |
Two | Before/After | No major limitation | One shows benefit | Asia Only | WHO case management by local health workers | 194 | 208 | 0.80 [0.47, 1.35] |
Two | Concurrent; Before/After | No major limitation | One shows benefit | Asia Only | WHO case management by local health workers | 194 | 285 | 0.94 [0.78, 1.12] |