From: Dietary management of childhood diarrhea in low- and middle-income countries: a systematic review

Study ID | Intervention diet | Control diet | Available outcome data | |||
---|---|---|---|---|---|---|

Duration | Stool output | Weight change | Treatment failure | |||

Comparison 1. Liquid feeds: Reduced lactose versus Regular lactose
Comparison of diets that include lactose-containing liquid feeds,
where the intervention liquid feed contains less lactose than the control liquid feed | ||||||

Bhatnagar 1998 | Fermented formula + rice-lentil-oil gruel | Milk formula + rice-lentil-oil gruel | Y | |||

Chew 1993 | Gradually increased concentration of milk formula | Full strength milk formula | Y | Y | Y | Y |

Ibanez 1986 | Acidified milk formula | Milk formula | Y | |||

Lifshitz 1991 | Diluted cow's milk | Cow's milk formula | Y | |||

Pichaipat 1986 | Gradually increased concentration of milk formula | Full strength milk formula | Y | |||

Ransome 1984 | Gradually increased concentration of cow's milk | Full-strength cow's milk | Y | Y | ||

Singh 1987 | Yogurt | Milk | Y | |||

Touhami 1989 | Half strength milk or milk formula | Full strength milk or milk formula | Y | Y | Y | Y |

Touhami 1992 | Fermented milk formula + cereals + vegetable soup | Milk formula + cereals + vegetable soup | Y | Y | Y | |

Comparison 2. Liquid feeds: Lactose-free versus Lactose-containing
Comparison of diets that include liquid feeds,
where the intervention liquid feed is lactose-free and the control liquid feed is lactose-containing | ||||||

Brown 1991 | i) Lactose-hydrolyzed powdered milk + corn syrup solids; ii) Lactose-hydrolyzed powdered milk + corn syrup solids, with wheat noodles | i) Powdered milk + corn syrup solids; ii) Powdered milk + corn syrup solids, with wheat noodles | Y | Y | Y | Y |

Fayad 1999 | Soy-based formula with sucrose | Soy-based formula with lactose | Y | Y | Y | |

Haffejee 1990 | Soy-based formula | Cow's milk formula | Y | |||

Lifshitz 1991 | i) Lactose-free sodium caseinate formula; ii) Lactose-free casein hydrolysate formula; iii) Soy-based formula | i) Diluted cow's milk; ii) Cow's milk formula | Y | |||

Lozano 1994 | Lactose-free casein-based formula plus non-milk food | Cow's milk formula plus same non-milk food | Y | Y | ||

Naidoo 1981 | Soy-based formula | Cow's milk formula | Y | |||

Penny 1989 | Lactose-hydrolyzed powdered milk + corn syrup solids | Powdered milk + corn syrup solids | Y | |||

Rajah 1988 | i) Lactose-free casein-based formula; ii) Soy-based formula; iii) Lactose-free hydrolyzed whey formula | Cow's milk formula | Y | Y | ||

Romer 1989 | Lactose-free semi-elemental formula | Cow's milk | Y | Y | ||

Simakachorn 2004 | Soy-based formula + rice gruel | Cow's milk formula + rice gruel | Y | Y | Y | Y |

Comparison 3. Lactose-free liquid feeds versus Lactose-containing mixed diets
Comparison of lactose-free liquid feeds with mixed diets containing lactose | ||||||

Alarcon 1991 | Soy-based formula | Potato flour + milk powder + carrot flour + veg oil + sugar | Y | |||

Bhutta 1991 | Soy-based formula | Rice + lentils + cottonseed oil + yogurt | Y | Y | Y | |

Bhutta 1994 | Soy-based formula | Rice + lentils + cottonseed oil + yogurt + diluted buffalo milk | Y | Y | Y | Y |

Brown 1991 | Lactose-hydrolyzed powdered milk + corn syrup solids | Powdered milk + corn syrup solids, with wheat noodles | Y | Y | Y | Y |

Comparison 4. Commercially prepared or specialized ingredients versus Home-available ingredients
Comparison of commercial preparations or specialized ingredients with diets comprised of home-available ingredients | ||||||

Alarcon 1991 | Soy-based formula | i) Wheat flour + pea flour + carrot flour + veg oil + cane sugar; ii) Potato flour + milk powder + carrot flour + veg oil + sugar | Y | |||

Alarcon 1992 | Rice + vegetable oil + soy protein isolate + corn syrup solids | Rice + vegetable oil +white beans | Y | |||

Bhan 1988 | Cow's milk formula | Rice + lentil + sugar + coconut oil | Y | Y | Y | |

Bhutta 1991 | Soy-based formula | Rice + lentils + cottonseed oil + yogurt | Y | Y | Y | |

Bhutta 1994 | Soy-based formula | Rice + lentils + cottonseed oil + yogurt + diluted buffalo milk | Y | Y | Y | Y |

Brown 1991 | i) Lactose-hydrolyzed powdered milk + corn syrup solids; ii) Lactose-hydrolyzed powdered milk + corn syrup solids, with wheat noodles | i) Powdered milk + corn syrup solids; ii) Powdered milk + corn syrup solids, with wheat noodles | Y | Y | Y | Y |

Carias 1999 | Soy-based formula | Lactose-free chicken-based formula | Y | Y | ||

Godard 1989 | Hydrolyzed lactalbumin + dextrin-maltrose + sunflower oil + carrots | Chicken + dextrin-maltrose + sunflower oil + carrots | Y | |||

Grange 1994 | Soy-based formula | Fermented maize flour + toasted cowpea flour + palm oil + sugar | Y | |||

Lifshitz 1991 | i) Lactose-free sodium caseinate formula; ii) Lactose-free casein hydrolysate formula; iii) Soy-based formula; iv) Cow's milk formula | Diluted cow's milk | Y | |||

Maulen-Radovan 1994 | Soy-based formula | Rice + chicken + carrots + beans + vegetable oil | Y | Y | Y | |

Nurko 1997 | i) Elemental formula: ii) Soy-based formula | Chicken + sugar + minerals + cooking oil | Y | Y | Y | Y |

Penny 1989 | Lactose-hydrolyzed powdered milk + corn syrup solids | Powdered milk + corn syrup solids | Y | |||

Romer 1989 | Lactose-free semi-elemental formula | Cow's milk | Y | Y | ||

Santosham 1990 | i) Soy-based formula; ii) Rice-based formula | Liquefied boiled rice | Y | Y | Y | Y |