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Table 2 Quality assessment of trials of antibiotics for the treatment of Shigella

From: Antibiotics for the treatment of Cholera, Shigella and Cryptosporidiumin children

Quality Assessment Summary of Findings
  Directness No of events  
No of studies Design Limitations Consistency Generalizability to population of interest Generalizability to intervention of interest Intervention Control Relative Risk (95%CI)
Clinical Failure (Antibiotics): Moderate Outcome Quality
03[2527] RCT No Control or placebo group, so used treatment failure rates All suggest benefit All studies were conducted in developing countries Hospital based 50   0.18 (0.1, 0.33) b
Bacteriological Failure (Antibiotics): Low Outcome Quality
04[2528] RCT No Control or placebo group, so used treatment failure rates All suggest benefit All studies except one were conducted in developing countries Hospital based 09   0.04 (0.01, 0.12) b