Antibiotics for the treatment of Cholera, Shigella and Cryptosporidiumin children

BMC Public Health

Table 2 Quality assessment of trials of antibiotics for the treatment of Shigella

Quality Assessment						Summary of Findings
				Directness		No of events
No of studies	Design	Limitations	Consistency	Generalizability to population of interest	Generalizability to intervention of interest	Intervention	Control	Relative Risk (95%CI)
Clinical Failure (Antibiotics): Moderate Outcome Quality
03[25–27]	RCT	No Control or placebo group, so used treatment failure rates	All suggest benefit	All studies were conducted in developing countries	Hospital based	50		0.18 (0.1, 0.33) ^b
*Bacteriological Failure (Antibiotics): Low Outcome Quality*
04[25–28]	RCT	No Control or placebo group, so used treatment failure rates	All suggest benefit	All studies except one were conducted in developing countries	Hospital based	09		0.04 (0.01, 0.12) ^b

ISSN: 1471-2458