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Table 5 Spirometry results with PFT pattern classification based upon new-onset respiratory symptoms (N = 220)

From: Respiratory symptoms and lung function 8–10 months after community exposure to chlorine gas: a public health intervention and cross-sectional analysis

  Mean NHANES % predicted (std) Below LLN and symptoms N = 110 (%) Below LLN and no symptoms N = 110 (%) Adjusted prevalence ratio*** (95% CI) p-value
Median    
FEV1 72.1 (21.5) 75 (68.2) 51 (46.4) 1.73 (1.11, 2.69) 0.015*
74.0
FVC 81.7 (23.6) 61(55.5) 49 (44.6) 1.66 (1.0, 2.77) 0.051
80.0
FEV1/FVC ratio % 82.4 (0.09) 15 (13.6) 9 (8.2) 2.25 (0.542, 9.34) 0.264
84.3
FEF25-75% 95.1 (39.1) 16 (14.6) 9 (8.2) 1.60 (0.50, 5.16) 0.431
93.2
Any abnormal parameter   82 (74.5) 64 (59.1) 1.62 (1.10, 2.39) 0.015*
Air-Flow pattern results** Normal 28 45  
Obstructive§ 12 8
        Mild 3 0
        Moderate 4 3
        Severe 5 3
        Very severe 0 2
        Restrictive§§ 46 34
        FEV1<LLN§§§ 24 23
  1. *Statistically significant at α = 0.05.
  2. **Normal = FEV1 and FVC ≥ LLN and FEV1/FVC ratio ≥ LLN.
  3. §Obstructive Spirometry Pattern = FEV1/FVC ratio < LLN.
  4. Mild: FEV1% predicted > 80% ,Moderate: 50% < FEV1 < 80% predicted, Severe: 30%< FEV1 <50% predicted, Very Severe: <30% predicted [39, 42].
  5. §§Restrictive Spirometry Pattern = FEV1, FVC, and FEV1/FVC Ratio > LLN.
  6. ***Covariate adjustment for age, sex, race, smoking and educational status.
  7. Adjusted prevalence ratios (PR), 95% confidence intervals, and Chi-square p-values for the association between report of respiratory symptoms and spirometry parameters below LLN.