House calls by community health workers and public health nurses to improve adherence to isoniazid monotherapy for latent tuberculosis infection: a retrospective study

Table 2 Latent tuberculosis patients completing INH treatment, stratified by type of follow-up

	Home follow-up^aN=986		Clinic follow-up^bN=2932
Patient characteristic	Completed^c	(%)^d	Completed	(%)	p-value^e	Risk ratio^f
All patients	887	(90.0)	2147	(73.2)	<0.001^g	1.23
Female	500	(91.1)	1068	(72.8)	0.99	1.25
Age categories:					<0.001
Age<6	135	(95.7)	129	(92.1)		1.04
Age 6 to <18	258	(93.1)	813	(84.1)		1.11
Age 18 to <35	347	(87.0)	685	(63.1)		1.38
Age 35 and older	147	(87.0)	520	(70.3)		1.24
Place of birth:					<0.001
Latin America	526	(88.9)	1124	(71.5)		1.24
Asia	227	(93.4)	652	(77.9)		1.20
USA	66	(88.0)	185	(69.0)		1.28
Africa	21	(95.5)	34	(70.8)		1.35
Europe	19	(95.0)	66	(80.5)		1.18
Unknown	28	(82.4)	86	(69.4)		1.19
Patient referral reason:					<0.001
Correctional/rehabilitation^h	7	(77.8)	106	(46.9)		1.66
TST converters/TB contactsⁱ	199	(90.5)	177	(77.3)		1.17
Postpartum women	51	(86.4)	94	(55.6)		1.55
TST+^j from screening	630	(90.3)	1770	(76.9)		1.17
Prescribed 9 months isoniazid^k	508	(91.5)	1226	(76.9)	<0.001	1.19

^aPatients assigned home-based follow-up with community health workers and public health nurses.
^bPatients with only clinic-based follow-up.
^cCompleted at least 6 months of isoniazid.
^dPercentage of number completed over total number in category, listed in Table 1.
^eCochran-Mantel-Haenszel test except as noted, all p-values adjusted for multiple comparisons.
^fUnadjusted “risk” ratio of completing treatment of home versus clinic follow-up for each patient category.
^gChi-square test.
^hPatients from correctional and drug and alcohol rehabilitation facilities.
ⁱRecent tuberculin skin test converters and household contacts to active tuberculosis cases.
^jTST+: Tuberculin skin test positive.
^kPrescribed 9 months instead of 6 months of isoniazid.

ISSN: 1471-2458