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Table 2 Insulin resistance and MetS components according to level of adiponectin, in eutrophic and obese children and adolescents

From: Adiponectin in eutrophic and obese children as a biomarker to predict metabolic syndrome and each of its components

  Adiponectin tertile (values)
Eutrophic subjects (n = 196) Obese subjects (n = 190)
3 2 1 3 2 1
Outcome variables (17.6-38.8) (12.6-17.5) (3.9-12.5) (13.4-27.5) (9.6-13.3) (1.4-9.5)
Insulin resistance       
Fasting insulin (μm/mL)       
Coefficient Referent 0.9 1.1 Referent 3.3 3.4
95% CI - −0.1; 1.9 0.1; 2.1 - −0.1; 6.5 0.2; 6.7
P - 0.083 0.032 - 0.053 0.039
HOMA-IR       
Coefficient Referent 0.2 0.3 Referent 0.6 0.8
95% CI - −0.1; 0.4 0.1; 0.5 - −0.2; 1.3 0.1; 1.6
P - 0.123 0.035 - 0.126 0.022
Components of MetS       
WC (cm)       
Coefficient Referent 0.9 3.1 Referent 4.9 5.9
95% CI - −0.6; 2.4 1.6; 4.6 - 2.1; 7.7 3.1; 8.7
P - 0.229 <0.001 - 0.001 <0.001
Blood pressure (mmHg)       
SBP       
Coefficient Referent 0.8 1.9 Referent 3.8 4.5
95% CI - −1.8; 3.5 −0.8; 4.5 - 0.9; 6.7 1.6; 7.3
P - 0.538 0.168 - 0.010 0.002
DBP       
Coefficient Referent 1.6 2.5 Referent 1.7 0.9
95% CI - −0.9;4.0 0.1; 5.0 - −1.0; 4.3 −1.8; 3.5
P - 0.213 0.043 - 0.585 0.738
Glucose (mg/dL)       
Coefficient Referent 0.1 0.5 Referent −0.4 3.9
95% CI - −3.6; 3.9 −3.2; 4.3 - −3.9; 3.1 −0.4; 7.4
P - 0.962 0.789 - 0.140 0.029
TGs (mg/dL)       
Coefficient Referent −2.3 4.8 Referent 14.4 27.3
95% CI - −13.5; 8.9 −6.2; 15.9 - −8.0; 36.8 4.9; 49.6
P - 0.931 0.391 - 0.206 0.017
HDL-C (mg/dL)       
Coefficient Referent 2.2 −0.3 Referent −1.3 −4.1
95% CI - −2.4; 6.8 −5.2; 4.5 - −5.3; 2.6 −8.1; 0.1
P - 0.351 0.894 - 0.511 0.048
  1. Values obtained through linear regression and adjusted for gender and body mass index percentile.
  2. Regression coefficients are change in outcome variables per tertile change in adiponectin concentration.
  3. MetS, metabolic syndrome; WC, waist circumference; SBP, systolic blood pressure; DBP, diastolic blood pressure; TGs, triglycerides; HDL-C, high-density lipoprotein cholesterol.