Skip to main content

Table 2 Insulin resistance and MetS components according to level of adiponectin, in eutrophic and obese children and adolescents

From: Adiponectin in eutrophic and obese children as a biomarker to predict metabolic syndrome and each of its components

 

Adiponectin tertile (values)

Eutrophic subjects (n = 196)

Obese subjects (n = 190)

3

2

1

3

2

1

Outcome variables

(17.6-38.8)

(12.6-17.5)

(3.9-12.5)

(13.4-27.5)

(9.6-13.3)

(1.4-9.5)

Insulin resistance

      

Fasting insulin (μm/mL)

      

Coefficient

Referent

0.9

1.1

Referent

3.3

3.4

95% CI

-

−0.1; 1.9

0.1; 2.1

-

−0.1; 6.5

0.2; 6.7

P

-

0.083

0.032

-

0.053

0.039

HOMA-IR

      

Coefficient

Referent

0.2

0.3

Referent

0.6

0.8

95% CI

-

−0.1; 0.4

0.1; 0.5

-

−0.2; 1.3

0.1; 1.6

P

-

0.123

0.035

-

0.126

0.022

Components of MetS

      

WC (cm)

      

Coefficient

Referent

0.9

3.1

Referent

4.9

5.9

95% CI

-

−0.6; 2.4

1.6; 4.6

-

2.1; 7.7

3.1; 8.7

P

-

0.229

<0.001

-

0.001

<0.001

Blood pressure (mmHg)

      

SBP

      

Coefficient

Referent

0.8

1.9

Referent

3.8

4.5

95% CI

-

−1.8; 3.5

−0.8; 4.5

-

0.9; 6.7

1.6; 7.3

P

-

0.538

0.168

-

0.010

0.002

DBP

      

Coefficient

Referent

1.6

2.5

Referent

1.7

0.9

95% CI

-

−0.9;4.0

0.1; 5.0

-

−1.0; 4.3

−1.8; 3.5

P

-

0.213

0.043

-

0.585

0.738

Glucose (mg/dL)

      

Coefficient

Referent

0.1

0.5

Referent

−0.4

3.9

95% CI

-

−3.6; 3.9

−3.2; 4.3

-

−3.9; 3.1

−0.4; 7.4

P

-

0.962

0.789

-

0.140

0.029

TGs (mg/dL)

      

Coefficient

Referent

−2.3

4.8

Referent

14.4

27.3

95% CI

-

−13.5; 8.9

−6.2; 15.9

-

−8.0; 36.8

4.9; 49.6

P

-

0.931

0.391

-

0.206

0.017

HDL-C (mg/dL)

      

Coefficient

Referent

2.2

−0.3

Referent

−1.3

−4.1

95% CI

-

−2.4; 6.8

−5.2; 4.5

-

−5.3; 2.6

−8.1; 0.1

P

-

0.351

0.894

-

0.511

0.048

  1. Values obtained through linear regression and adjusted for gender and body mass index percentile.
  2. Regression coefficients are change in outcome variables per tertile change in adiponectin concentration.
  3. MetS, metabolic syndrome; WC, waist circumference; SBP, systolic blood pressure; DBP, diastolic blood pressure; TGs, triglycerides; HDL-C, high-density lipoprotein cholesterol.