Diagnosis | Female IBS cases N = 353 | Female controls N = 1481 | Male IBS cases N = 140 | Male controls N = 1292 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
n | % | n | % | OR | CI 95% | n | % | n | % | OR | CI 95% | |
Reflux complaints (GERD) | 73 | 21.1 | 77 | 5.5 | 4.75 | 3.37–6.71*** | 21 | 15.0 | 70 | 5.4 | 3.08 | 1.83–5.20*** |
Complaints with known ulcer | 5 | 1.4 | 5 | 0.3 | 4.24 | 1.22–14.73* | 4 | 2.9 | 11 | 1.0 | 3.42 | 1.08–10.90* |
Functional dyspepsia | 134 | 38.1 | 128 | 8.6 | 6.47 | 4.88–8.57*** | 53 | 35.7 | 92 | 7.1 | 7.94 | 5.32–11.88** |
Inflammatory bowel disease | 28 | 7.9 | 62 | 4.2 | 1.97 | 1.24–3.13*** | 6 | 4.3 | 41 | 3.2 | 1.37 | 0.57–3.28 |
Diverticulitis in the bowel | 33 | 9.3 | 12 | 0.8 | 12.62 | 6.44–24.71 *** | 10 | 3.6 | 55 | 4.3 | 9.86 | 4.03–24.13*** |
Haemorrhoids and rectal abscesses | 25 | 7.1 | 67 | 4.5 | 1.61 | 1.00–2.59 | 22 | 15.7 | 58 | 4.5 | 3.97 | 2.35–6.71*** |
Liver diseases | 3 | 0.8 | 5 | 0.3 | 2.53 | 0.60–10.65 | 0 | 0 | 17 | 1.3 | – | – |
Gallstone, gallbladder inflammation and other diseases in the gallbladder area | 30 | 8.5 | 55 | 3.7 | 2.41 | 1.52–3.82** | 8 | 5.7 | 20 | 1.5 | 3.85 | 1.67–8.92** |
Lactose intolerance | 1 | 0.3 | 9 | 0.6 | 0.46 | 0.06–3.68 | 2 | 1.4 | 2 | 0.2 | 9.35 | 1.31–66.88* |
Coeliac disease | 4 | 1.1 | 13 | 0.9 | 1.39 | 0.42–3.99 | 3 | 2.1 | 4 | 0.3 | 7.05 | 1.56–31.83* |
Irritable bowel syndrome 1 | 30 | 8.5 | 8 | 0.5 | – | – | 6 | 4.3 | 5 | 0.4 | – | – |
Gastroenteritis | 4 | 1.1 | 5 | 0.3 | 3.38 | 0.90–12.66 | 1 | 0.7 | 5 | 0.4 | 1.85 | 0.21–15.96 |
Cancer in the abdominal tract 2 | 8 | 2.3 | 5 | 0.3 | 6.84 | 2.26–21.05 *** | 2 | 1.4 | 6 | 0.5 | 2.55 | 0.62–15.54 |
Benign tumours in the abdominal tracts | 18 | 5.1 | 9 | 0.6 | 8.79 | 3.92–19.73 *** | 4 | 2.9 | 10 | 0.8 | 3.77 | 1.17–12.18* |
Miscellaneous gastrointestinal complaints | 6 | 1.7 | 18 | 1.2 | 1.40 | 0.55–3.57 | 6 | 4.3 | 26 | 2.0 | 2.18 | 0.88–5.39 |