Diagnosis | Female IBS cases N = 353 | Female controls N = 1481 | Male IBS cases N = 140 | Male controls N = 1292 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
n | % | n | % | OR | CI 95% | n | % | n | % | OR | CI 95% | |
Worry about serious disease | 73 | 21.1 | 205 | 14.0 | 1.62 | 1.21–2.18** | 20 | 14.3 | 62 | 5.1 | 3.30 | 1.93–5.66*** |
Cardiovascular complaints Stroke, chest pain UNS | 180 | 51.1 | 288 | 19.4 | 4.31 | 3.37–5.51*** | 89 | 64.1 | 331 | 26.1 | 5.06 | 3.51–7.31*** |
Hypertension | 90 | 25.5 | 226 | 15.3 | 1.90 | 1.44–2.51 ** | 36 | 26.0 | 232 | 18.1 | 1.58 | 1.05–2.37** |
Diabetes 1 | 30 | 8.5 | 90 | 6.1 | 1.43 | 0.93–2.21 | 12 | 8.6 | 129 | 10 | 0.84 | 0.45–1.57 |
High Cholesterol | 43 | 12.2 | 95 | 6.4 | 2.02 | 1.38–2.96 ** | 33 | 23.6 | 151 | 11.7 | 2.33 | 1.52–3.57*** |
Obesity | 16 | 4.5 | 67 | 4.5 | 1.00 | 0.57–1.75 | 7 | 0.5 | 42 | 3.3 | 1.56 | 0.69–3.56 |
Thyroid diseases | 52 | 15.0 | 133 | 8.9 | 1.75 | 1.24–2.47 ** | 5 | 3.6 | 55 | 4.3 | 0.83 | 0.33–2.11 |
Asthma/allergy | 114 | 32.2 | 373 | 25.1 | 1.42 | 1.10–1.83 * | 38 | 27.1 | 228 | 18.0 | 1.74 | 1.16–2.59* |
Eczema | 58 | 16.4 | 123 | 8.3 | 2.17 | 1.55–3.04*** | 19 | 13.6 | 86 | 6.6 | 2.20 | 1.29–3.74* |
Obstructive lung disease | 10 | 2.8 | 22 | 1.5 | 1.93 | 0.91– 4.12 | 8 | 5.7 | 12 | 1.0 | 6.46 | 2.60–16.10* |
Arthritis | 51 | 14.4 | 92 | 6.2 | 2.55 | 1.77–3.67*** | 22 | 15.7 | 79 | 6.1 | 2.86 | 1.72.4.72* |
Musculoskeletal problems | 104 | 29.5 | 263 | 18.0 | 1.93 | 1.48–2.52*** | 40 | 28.6 | 183 | 14.5 | 2.42 | 1.63–3.61*** |
Myalgia/rheumatism UNS | 211 | 60.0 | 573 | 28.7 | 2.35 | 1.86–2.99*** | 65 | 46.4 | 345 | 27.0 | 2.38 | 1.67–3.39*** |
Pain and suffering UNS | 48 | 14.1 | 120 | 8.1 | 1.78 | 1.25–2.55** | 19 | 13.6 | 72 | 5.6 | 2.66 | 1.55–4.56** |
Migraine/headache | 142 | 40.2 | 310 | 21.0 | 2.54 | 1.99–3.25*** | 39 | 28.1 | 135 | 10.4 | 3.31 | 2.20–4.99*** |
Mental problems 2 | 213 | 60.0 | 275 | 19.1 | 6.67 | 5.19–8.56*** | 47 | 33.6 | 194 | 15.0 | 2.86 | 1.81–3.45*** |
Stress | 68 | 19.3 | 244 | 16.5 | 1.20 | 0.90–1.63 | 19 | 14.0 | 97 | 7.5 | 1.93 | 1.14–3.27* |
Tinnitus | 15 | 4.2 | 44 | 3.0 | 1.45 | 0.80–2.64 | 5 | 3.6 | 38 | 3.0 | 1.22 | 0.47–3.20 |
Eating disorder | 1 | 0.3 | 11 | 0.7 | 0.38 | 0.05–2.95 | 3 | 2.1 | 1 | 0.01 | 28.27 | 2.92–273.6*** |
Cancer | 14 | 4.1 | 16 | 1.1 | 3.78 | 1.83–7.83*** | 1 | 0.7 | 5 | 0.4 | 1.85 | 0.22–15.96 |
Cold, flu/respiratory infections | 56 | 16.1 | 121 | 8.2 | 2.12 | 1.51–2.98*** | 20 | 14.3 | 55 | 4.3 | 3.75 | 2.17–6.47*** |
Infection in the urinary tract | 48 | 14.1 | 84 | 6.1 | 2.62 | 1.80–3.81*** | 16 | 11.4 | 28 | 2.2 | 5.82 | 3.08–11.06*** |
Disease in the kidney | 11 | 3.1 | 6 | 0.4 | 7.91 | 2.90–21.53** | 3 | 2.1 | 12 | 0.9 | 2.34 | 0.65–8.38 |
Gynaecological/pregnancy/ 3Urological/prostate problems4 | 19 | 5.4 | 64 | 4.3 | 1.26 | 0.74 –2.13 | 3 | 2.1 | 9 | 0.7 | 3.12 | 0.83–11.67 |
Fatigue and malaise | 117 | 33.1 | 225 | 15.2 | 2.77 | 2.13–3.60*** | 31 | 22.1 | 101 | 8.0 | 3.35 | 2.14–5.25*** |
Psychosocial factors in daily life | 5 | 1.4 | 11 | 0.7 | 1.85 | 0.87–3.92 | 2 | 1.4 | 10 | 0.8 | 1.85 | 0.21–4.66 |
Investigation of serious illness | 16 | 4.5 | 19 | 2.0 | 3.65 | 1.86–7.18*** | 1 | 0.7 | 7 | 0.5 | 1.32 | 0.16–10.83 |
Miscellaneous diseases | 185 | 52.4 | 362 | 24.4 | 3.40 | 2.68–4.33*** | 52 | 37.1 | 266 | 21.1 | 2.80 | 1.58–3.29*** |