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Table 2 Eight-year prevalence of non-gastrointestinal morbidity in IBS-patients and controls

From: Patients with irritable bowel syndrome are more burdened by co-morbidity and worry about serious diseases than healthy controls- eight years follow-up of IBS patients in primary care

Diagnosis

Female IBS cases N = 353

Female controls N = 1481

  

Male IBS cases N = 140

Male controls N = 1292

  
 

n

%

n

%

OR

CI 95%

n

%

n

%

OR

CI 95%

Worry about serious disease

73

21.1

205

14.0

1.62

1.21–2.18**

20

14.3

62

5.1

3.30

1.93–5.66***

Cardiovascular complaints Stroke, chest pain UNS

180

51.1

288

19.4

4.31

3.37–5.51***

89

64.1

331

26.1

5.06

3.51–7.31***

Hypertension

90

25.5

226

15.3

1.90

1.44–2.51 **

36

26.0

232

18.1

1.58

1.05–2.37**

Diabetes 1

30

8.5

90

6.1

1.43

0.93–2.21

12

8.6

129

10

0.84

0.45–1.57

High Cholesterol

43

12.2

95

6.4

2.02

1.38–2.96 **

33

23.6

151

11.7

2.33

1.52–3.57***

Obesity

16

4.5

67

4.5

1.00

0.57–1.75

7

0.5

42

3.3

1.56

0.69–3.56

Thyroid diseases

52

15.0

133

8.9

1.75

1.24–2.47 **

5

3.6

55

4.3

0.83

0.33–2.11

Asthma/allergy

114

32.2

373

25.1

1.42

1.10–1.83 *

38

27.1

228

18.0

1.74

1.16–2.59*

Eczema

58

16.4

123

8.3

2.17

1.55–3.04***

19

13.6

86

6.6

2.20

1.29–3.74*

Obstructive lung disease

10

2.8

22

1.5

1.93

0.91– 4.12

8

5.7

12

1.0

6.46

2.60–16.10*

Arthritis

51

14.4

92

6.2

2.55

1.77–3.67***

22

15.7

79

6.1

2.86

1.72.4.72*

Musculoskeletal problems

104

29.5

263

18.0

1.93

1.48–2.52***

40

28.6

183

14.5

2.42

1.63–3.61***

Myalgia/rheumatism UNS

211

60.0

573

28.7

2.35

1.86–2.99***

65

46.4

345

27.0

2.38

1.67–3.39***

Pain and suffering UNS

48

14.1

120

8.1

1.78

1.25–2.55**

19

13.6

72

5.6

2.66

1.55–4.56**

Migraine/headache

142

40.2

310

21.0

2.54

1.99–3.25***

39

28.1

135

10.4

3.31

2.20–4.99***

Mental problems 2

213

60.0

275

19.1

6.67

5.19–8.56***

47

33.6

194

15.0

2.86

1.81–3.45***

Stress

68

19.3

244

16.5

1.20

0.90–1.63

19

14.0

97

7.5

1.93

1.14–3.27*

Tinnitus

15

4.2

44

3.0

1.45

0.80–2.64

5

3.6

38

3.0

1.22

0.47–3.20

Eating disorder

1

0.3

11

0.7

0.38

0.05–2.95

3

2.1

1

0.01

28.27

2.92–273.6***

Cancer

14

4.1

16

1.1

3.78

1.83–7.83***

1

0.7

5

0.4

1.85

0.22–15.96

Cold, flu/respiratory infections

56

16.1

121

8.2

2.12

1.51–2.98***

20

14.3

55

4.3

3.75

2.17–6.47***

Infection in the urinary tract

48

14.1

84

6.1

2.62

1.80–3.81***

16

11.4

28

2.2

5.82

3.08–11.06***

Disease in the kidney

11

3.1

6

0.4

7.91

2.90–21.53**

3

2.1

12

0.9

2.34

0.65–8.38

Gynaecological/pregnancy/ 3Urological/prostate problems4

19

5.4

64

4.3

1.26

0.74 –2.13

3

2.1

9

0.7

3.12

0.83–11.67

Fatigue and malaise

117

33.1

225

15.2

2.77

2.13–3.60***

31

22.1

101

8.0

3.35

2.14–5.25***

Psychosocial factors in daily life

5

1.4

11

0.7

1.85

0.87–3.92

2

1.4

10

0.8

1.85

0.21–4.66

Investigation of serious illness

16

4.5

19

2.0

3.65

1.86–7.18***

1

0.7

7

0.5

1.32

0.16–10.83

Miscellaneous diseases

185

52.4

362

24.4

3.40

2.68–4.33***

52

37.1

266

21.1

2.80

1.58–3.29***

  1. 1. Both insulin dependent and insulin independent diabetes. 2. Includes anxiety, depression, sleeping problems, worries etc. 3. Concerns women 4. Concerns men. ***p = 0.001, **P = 0.01, *p = 0.05.