12
|
1700 h (check in)
|
Blood, urine
|
Measure BP, PR, RR and temperature; abbreviated physical examination and medical history; illicit drug, alcohol and cotinine testing; pregnancy testing; collection of diary and cigarette butts; dinner
|
1900 h
|
None
|
Start first 24 h urine collection, monitoring of cigarette consumption and collection of filters
|
2100 h
|
None
|
Snack
|
13
|
0700 h
|
Blood
|
Measure BP, PR, RR and temperature; blood collection for creatinine in serum, biomarkers and gene expression
|
0800 h
|
None
|
Breakfast
|
To be scheduled
|
None
|
Assess smoking behavioura
|
1000 h
|
None
|
Administer sensory, quality-of-life and diet and lifestyle questionnairesb
|
1200 h
|
None
|
Lunch
|
1500 h
|
None
|
Measure exhaled CO
|
1700 h
|
Saliva
|
Saliva cotinine testing; dinner
|
1900 h
|
None
|
End first and start second 24 h urine collection, monitoring of cigarette consumption and collection of filters
|
2100 h
|
None
|
Snack
|
14
|
0700 h
|
Blood
|
Measure BP, PR, RR and temperature; blood collection for creatinine in serum, biomarkers and gene expression
|
0800 h
|
None
|
Breakfast
|
To be scheduled
|
None
|
Assess smoking behavioura
|
1100 h
|
None
|
Pulmonary-function test
|
1200 h
|
None
|
Lunch
|
1500 h
|
None
|
Measure exhaled CO
|
1700 h
|
Saliva
|
Saliva cotinine testing; dinner
|
1900 h
|
None
|
End second 24 h urine collection, monitoring of cigarette consumption and collection of filters; switch to next assigned product
|
2100 h
|
None
|
Snack
|
15
|
0700 h
|
None
|
Measure BP, PR, RR and temperature
|
0800 h
|
None
|
Breakfast
|
1000 h
|
None
|
Administer sensory questionnaire
|
1200 h
|
None
|
Lunch
|
1700 h
|
None
|
Dinner
|
1900 h
|
None
|
End filter collection; dispense interventional products and cigarette butt collection tins for use at home, remind participants of instructions for diet and completion of diaries
|