A single-blinded, single-centre, controlled study in healthy adult smokers to identify the effects of a reduced toxicant prototype cigarette on biomarkers of exposure and of biological effect versus commercial cigarettes

Table 3 Investigational products

Study period	Control group	Test group
Days 1–14	Lucky Strike Silver (ID W861) with mono CA filter, cork-print tipping and commercial tobacco blend	Lucky Strike Silver (ID W861) with mono CA filter, cork-print tipping and commercial tobacco blend
Days 1–14	Yields using ISO methodology: 7 mg tar, 0.6 mg nicotine, 8 mg CO	Yields using ISO methodology: 7 mg tar, 0.6 mg nicotine, 8 mg CO
Days 15–183	Lucky Strike Silver (ID H285) with mono CA filter, white tipping and commercial tobacco blend	RTP (ID G429) with triple CA/CR20/charcoal filter^a, white tipping and study tobacco blend (20% non-tobacco sheet, 50% treated tobacco and 30% commercial blend).
Days 15–183	Yields using ISO methodology: 7 mg tar, 0.6 mg nicotine, 8 mg CO	Yields using ISO methodology: 7 mg tar, 0.7 mg nicotine, 8 mg CO ^a

ID, study identification code, CA, cellulose acetate, CR20, amine-functionalised resin filter additive, CO, carbon monoxide, RTP, reduced-toxicant prototype cigarette, ISO, International Organisation for Standardisation. ^ato be confirmed.

ISSN: 1471-2458