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Table 4 Off-label medicine use by ATC-classes and age groups, KiGGS 2003-2006

From: Off-label medicine use in children and adolescents: results of a population-based study in Germany

ATC-class

0-2 years

3-6 years

7-10 years

11-13 years

14-17 years

n (%)

n (%)

n (%)

n (%)

n (%)

A00 Alimentary tract and metabolism

328 (21.3)

255 (49.5)

172 (50.0)

108 (47.8)

130 (43.0)

B00 Blood and blood forming organs

2 (13.3)

1 (14.3)

2 (50.0)

10 (52.6)

9 (32.1)

C00 Cardiovascular system

3 (100)

2 (40.0)

9 (64.3)

9 (90.0)

16 (61.5)

D00 Dermatologicals

102 (26.6)

106 (30.1)

110 (31.0)

75 (37.1)

92 (32.1)

G00 Genito urinary system and sex hormones

4 (66.7)

1 (10.0)

6 (50.0)

2 (25.0)

53 (11.5)

H00 Systemic hormon. preparations excl. sex hormones and insulins

3 (14.3)

11 (19.3)

7 (13.7)

7 (9.5)

14 (15.2)

J00 Antiinfectives for systemic use

29 (32.2)

41 (36.6)

18 (30.5)

15 (31.9)

19 (28.8)

L00 Antineoplastic and immunmodulating agents

7 (70.0)

16 (57.1)

8 (42.1)

6 (42.9)

7 (50.0)

M00 Musculo-skeletal system

13 (25.5)

17 (23.3)

18 (16.8)

21 (18.9)

28 (13.4)

N00 Nervous system

20 (12.7)

21 (20.2)

51 (25.5)

39 (16.5)

44 (11.1)

P00 Antiparasitic products insecticides and repellents

1 (33.3)

1 (20.0)

1 (14.3)

0

 

R00 Respiratory system

356 (39.1)

493 (40.4)

288 (35.7)

146 (30.7)

133 (27.7)

S00 Sensory organs

30 (56.6)

30 (42.3)

13 (61.9)

11 (36.7)

8 (32.0)

V00 Various

16 (16.3)

6 (25.0)

7 (16.7)

1 (5.6)

5 (13.9)

Z00 Homoeopathics

41 (23.2)

47 (20.3)

37 (19.2)

22 (20.6)

22 (23.9)

TOTAL n = 12,667

954 (27.1)

1048 (37.3)

747 (33.5)

473 (29.8)

580 (23.0)