From: Off-label medicine use in children and adolescents: results of a population-based study in Germany
ATC-class | 0-2 years | 3-6 years | 7-10 years | 11-13 years | 14-17 years |
---|---|---|---|---|---|
n (%) | n (%) | n (%) | n (%) | n (%) | |
A00 Alimentary tract and metabolism | 328 (21.3) | 255 (49.5) | 172 (50.0) | 108 (47.8) | 130 (43.0) |
B00 Blood and blood forming organs | 2 (13.3) | 1 (14.3) | 2 (50.0) | 10 (52.6) | 9 (32.1) |
C00 Cardiovascular system | 3 (100) | 2 (40.0) | 9 (64.3) | 9 (90.0) | 16 (61.5) |
D00 Dermatologicals | 102 (26.6) | 106 (30.1) | 110 (31.0) | 75 (37.1) | 92 (32.1) |
G00 Genito urinary system and sex hormones | 4 (66.7) | 1 (10.0) | 6 (50.0) | 2 (25.0) | 53 (11.5) |
H00 Systemic hormon. preparations excl. sex hormones and insulins | 3 (14.3) | 11 (19.3) | 7 (13.7) | 7 (9.5) | 14 (15.2) |
J00 Antiinfectives for systemic use | 29 (32.2) | 41 (36.6) | 18 (30.5) | 15 (31.9) | 19 (28.8) |
L00 Antineoplastic and immunmodulating agents | 7 (70.0) | 16 (57.1) | 8 (42.1) | 6 (42.9) | 7 (50.0) |
M00 Musculo-skeletal system | 13 (25.5) | 17 (23.3) | 18 (16.8) | 21 (18.9) | 28 (13.4) |
N00 Nervous system | 20 (12.7) | 21 (20.2) | 51 (25.5) | 39 (16.5) | 44 (11.1) |
P00 Antiparasitic products insecticides and repellents | 1 (33.3) | 1 (20.0) | 1 (14.3) | 0 | |
R00 Respiratory system | 356 (39.1) | 493 (40.4) | 288 (35.7) | 146 (30.7) | 133 (27.7) |
S00 Sensory organs | 30 (56.6) | 30 (42.3) | 13 (61.9) | 11 (36.7) | 8 (32.0) |
V00 Various | 16 (16.3) | 6 (25.0) | 7 (16.7) | 1 (5.6) | 5 (13.9) |
Z00 Homoeopathics | 41 (23.2) | 47 (20.3) | 37 (19.2) | 22 (20.6) | 22 (23.9) |
TOTAL n = 12,667 | 954 (27.1) | 1048 (37.3) | 747 (33.5) | 473 (29.8) | 580 (23.0) |