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Table 2 Off-label and in-label medicine use by origin of medicines, KiGGS 2003-2006

From: Off-label medicine use in children and adolescents: results of a population-based study in Germany

Drug use categories Origin of medicines (n = 12,587*)
Prescribed OTC Other sources
n % 95% CI n % 95% CI n % 95% CI
Off-label medicine use 2,344 29.9 (28.9-30.9) 925 30.3 (28.7-31.9) 515 30.6 (28.5-32.9)
   ➢ Indication 376 4.8 (4.3-5.2) 106 3.5 (2.9-4.2) 56 3.3 (2.6-4.3)
   ➢ Age 326 4.2 (3.7-4.6) 100 3.3 (2.7-4.0) 45 2.7 (2.0-3.6)
   ➢ Under-dosing 1,263 16.1 (15.3-16.9) 590 19.3 (18.0-20.8) 339 20.2 (18.3-22.2)
   ➢ Over-dosing 379 4.8 (4.4-5.3) 129 4.2 (3.6-5.0) 75 4.5 (3.6-5.6)
In-label medicine use 5,508 70.1 (69.1-71.1) 2,129 69.7 (68.1-71.3) 1,166 69.4 (67.1-71.5)
  1. * Discrepancy to total n = 12,667 because of missing data (n = 80). OTC = Over the Counter.