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Table 2 Off-label and in-label medicine use by origin of medicines, KiGGS 2003-2006

From: Off-label medicine use in children and adolescents: results of a population-based study in Germany

Drug use categories

Origin of medicines (n = 12,587*)

Prescribed

OTC

Other sources

n

%

95% CI

n

%

95% CI

n

%

95% CI

Off-label medicine use

2,344

29.9

(28.9-30.9)

925

30.3

(28.7-31.9)

515

30.6

(28.5-32.9)

   ➢ Indication

376

4.8

(4.3-5.2)

106

3.5

(2.9-4.2)

56

3.3

(2.6-4.3)

   ➢ Age

326

4.2

(3.7-4.6)

100

3.3

(2.7-4.0)

45

2.7

(2.0-3.6)

   ➢ Under-dosing

1,263

16.1

(15.3-16.9)

590

19.3

(18.0-20.8)

339

20.2

(18.3-22.2)

   ➢ Over-dosing

379

4.8

(4.4-5.3)

129

4.2

(3.6-5.0)

75

4.5

(3.6-5.6)

In-label medicine use

5,508

70.1

(69.1-71.1)

2,129

69.7

(68.1-71.3)

1,166

69.4

(67.1-71.5)

  1. * Discrepancy to total n = 12,667 because of missing data (n = 80). OTC = Over the Counter.