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Table 2 Multivariable analysis of factors associated with infants measles log 10 antibody responses at one year of age, following immunisation at 9 months

From: Factors affecting the infant antibody response to measles immunisation in Entebbe-Uganda

  Univariable analysis Multivariable analysis1
Explanatory variable Status Proportion (%) with protective antibody levels P-value2 Mean (SD) Log10antibody levels Difference (95% confidence interval) P-value Difference (95% confidence interval) P-value3
Gravidity 1 147/184 (80) 0.009 2.54 (0.48)   0.06   0.06
2–4 310/413 (75)   2.55 (0.51) 0.01 (−0.08, 0.10)   0.01 (−0.08, 0.10)  
5+ 73/114 (64)   2.42 (0.57) −0.12 (−0.24, 0.001)   −0.12(−0.24, 0.001)  
Maternal malaria infection No 484/646 (75) 0.3 2.54 (0.51)   0.09   0.05
Yes 37/54 (68)   2.41 (0.67) −0.13 (−0.27, 0.02)   −0.14 (−0.29, 0.002)  
Infant asymptomatic malaria at age one year No 486/647 (75) 0.07 2.54 (0.51)   0.003   0.003
Yes 25/40 (62)   2.29 (0.59) −0.25 (−0.42, -0.09)   −0.25 (−0.41, -0.08)  
Infant HIV Unexposed 482/637 (76) 0.003 2.54 (0.50)   0.002   0.003
Exposed, uninfected 44/62 (71)   2.48 (0.54) −0.06 (−0.19, 0.07)   −0.05 (−0.18, 0.09)  
Infected 4/12 (33)   2.02 (0.85) −0.52( −0.82, -0.23)   −0.50 (−0.80, -0.21)  
Weight-for length/height (wasting) No 514/684 (75) 0.06 2.54 (0.50)   0.01   0.04
  Yes 16/27 (59)   2.28 (0.78) −0.26 (−0.45, -0.06)   −0.21 (−0.41, -0.01)  
  1. SD Standard deviation; 1in multivariable analyses, maternal asymptomatic malaria was adjusted for gravidity, infant asymptomatic malaria and HIV were adjusted for each other and for gravidity and maternal malaria infection, wasting was adjusted for all other variables in the table 2chi2 test 3likelihood ratio test.