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Table 4 Unadjusted and adjusted odds ratios of asthma and allergic symptoms in children aged 7–8 and 13–14 from the Greek-Cypriot and Turkish-Cypriot communities in relation to risk factors projected in the hygiene hypothesis

From: Prevalence of asthma and allergies in children from the Greek-Cypriot and Turkish-Cypriot communities in Cyprus: a bi-communal cross-sectional study

 

Children 7–8 years of age

Current wheeze

Severe asthma

Current eczema

Current Rhinoconjuctivitis

Unadjusted OR (95%CI)

Adjusted OR† (95% CI)

Unadjusted OR (95% CI)

Adjusted OR† (95% CI)

Unadjusted OR (95% CI)

Adjusted OR† (95% CI)

Unadjusted OR(95% CI)

Adjusted OR† (95% CI)

Older sibling

        

  1 (Vs None)

0.86 (0.69, 1.07)

0.76 (0.59, 0.97)

1.08 (0.77, 1.51)

0.80 (0.55, 1.16)

0.87 (0.63, 1.20)

0.70 (0.48, 1.00)

0.87 (0.61. 1.23)

0.76 (0.51, 1.11)

  ≥2 (Vs None)

0.83 (0.63, 1.08)

0.72 (0.53, 0.98)

0.82 (0.52, 1.27)

0.56 (0.33, 0.91)

0.48 (0.29, 0.75)

0.36 (0.20, 0.61)

0.97 (0.63, 1.46)

0.77 (0.47, 1.22)

Farm animal at home

1.11 (0.62, 1.87)

0.99 (0.54, 1.72)

1.13 (0.46, 2.36)

0.97 (0.38, 2.10)

1.26 (0.48, 2.74)

1.33 (0.49, 3.04)

1.26 (0.52, 2.62)

1.02 (0.40, 2.21)

Area of residence

        

  Sub-rural (Vs Rural)

1.04 (0.79, 1.37)

1.09 (0.82, 1.45)

1.40 (0.92, 2.13)

1.49 (0.96, 2.31)

1.01 (0.64, 1.61)

1.12 (0.69, 1.80)

1.03 (0.67, 1.57)

1.08 (0.70, 1.68)

  Urban (Vs Rural)

0.87 (0.69, 1.12)

0.87 (0.67, 1.13)

1.04 (0.70, 1.54)

1.02 (0.67, 1.56)

1.20 (0.82, 1.79)

1.20 (0.79, 1.85)

0.89 (0.61, 1.30)

0.83 (0.56, 1.26)

Bedroom sharing

1.09 (0.90, 1.33)

1.20 (0.95, 1.52)

1.61 (1.18, 2.20)

1.69 (1.17, 2.43)

1.00 (0.75, 1.36)

1.29 (0.90, 1.86)

1.16 (0.85, 1.58)

1.17 (0.82, 1.69)

Nursery attendance

1.25 (0.84, 1.96)

1.28 (0.85, 2.03)

0.81 (0.47, 1.53)

0.85 (0.49, 1.62)

0.88 (0.53, 1.58)

0.84 (0.49, 1.52)

0.97 (0.55, 1.92)

1.05 (0.58, 2.10)

 

Children 13–14 years of age

 

Current wheeze

Severe asthma

Current eczema

Current Rhinoconjuctivitis

 

Unadjusted OR (95%CI)

Adjusted OR ‡ (95% CI)

Unadjusted OR (95% CI)

Adjusted OR ‡ (95% CI)

Unadjusted OR (95% CI)

Adjusted OR ‡ (95% CI)

Unadjusted OR (95% CI)

Adjusted OR ‡ (95% CI)

Older sibling

        

  1 (Vs None)

0.87 (0.65, 1.16)

0.87 (0.64, 1.19)

1.00 (0.67, 1.48)

1.03 (0.66, 1.58)

0.86 (0.54, 1.37)

0.84 (0.50, 1.39)

1.33 (1.00. 1.77)

1.29 (0.95, 1.76)

  ≥2 (Vs None)

0.82 (0.59, 1.13)

0.90 (0.64, 1.26)

0.86 (0.53, 1.35)

0.95 (0.57, 1.55)

1.43 (0.92, 2.24)

1.40 (0.86, 2.27)

1.59 (1.17, 2.15)

1.41 (1.02, 1.96)

Farm animal at home

0.35 (0.04, 0.94)

0.39 (0.10, 1.05)

0.94 (0.28, 2.30)

0.78 (0.19, 2.19)

0.88 (0.21, 2.42)

0.94 (0.23, 2.66)

1.15 (0.58, 2.08)

1.03 (0.49, 1.94)

Area of residence

        

  Sub-rural (Vs Rural)

1.52 (1.05, 2.20)

1.64 (1.11, 2.42)

1.61 (0.97, 2.71)

1.77 (1.02, 3.10)

0.99 (0.56, 1.72)

1.04 (0.56, 1.88)

0.68 (0.47, 0.96)

0.75 (0.51, 1.10)

  Urban (Vs Rural)

1.37 (1.00, 1.90)

1.44 (1.02, 2.05)

1.42 (0.91, 2.26)

1.46 (0.90, 2.43)

1.03 (0.66, 1.65)

1.29 (0.80, 2.12)

0.89 (0.68, 1.16)

0.98 (0.73, 1.33)

  1. † Adjusted for each other as well as community (G/C and T/C), gender, parents’ nationality, parents’ level of education, family history of allergies, animals at home, passive smoking, maternal smoking during pregnancy, mode of delivery, birth weight and exclusive breastfeeding duration.
  2. ‡ Adjusted for each other as well as community (G/C and T/C), gender, parents’ nationality, parents’ level of education, family history of allergies, animals at home and passive smoking at home. Bedroom sharing, nursery attendance, maternal smoking during pregnancy, mode of delivery, birth weight and exclusive breastfeeding duration were not available for the 13–14 year-old children.