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Table 3 Association between socio-demographic and clinical characteristics and a positive cervical screening test among HIV-infected women

From: Cervical cancer risk factors among HIV-infected Nigerian women

 

Univariate

Multivariate

 

RR (95%CI)

p-value

RR (95%CI)

p-value

Socio-demographic characteristics

    

Age category (years)

 

<0.0001*

 

0.0005*

   <30 (ref)

1.0

 

1.0

 

   30–34

0.8 (0.5–1.1)

 

(0.6–1.3)

 

   35–39

0.6 (0.4–0.9)

 

(0.5–1.1)

 

   ≥40

0.3 (0.2–0.5)

 

0.4 (0.2–0.7)

 

Age at first sexual intercourse (years)

 

0.06*

 

0.05*

   <15 (ref)

1.0

 

1.0

 

   15–19

0.9 (0.5–1.6)

 

0.8 (0.5–1.3)

 

   20–24

0.7 (0.4–1.3)

 

0.6 (0.4–1.1)

 

   ≥25

0.6 (0.2–1.3)

 

0.5 (0.2–1.2)

 

Number of sexual partners

 

0.2*

  

   ≤2 (ref)

1.0

   

   3–4

1.2 (0.5–2.8)

   

   ≥5

2.1 (0.7–6.1)

   

Total number of pregnancies

 

0.03*

 

0.1*

   0–2 (ref)

1.0

 

1.0

 

   3–4

0.8 (0.5–1.1)

 

0.7 (0.5–1.1)

 

   5–6

0.6 (0.4–1.0)

 

0.6 (0.4–1.1)

 

   ≥7

0.7 (0.4–1.1)

 

0.7 (0.4–1.3)

 

Total number of abortions

 

0.06*

 

0.007*

   0–2 (ref)

1.0

 

1.0

 

   3–4

1.5 (1.0–2.1)

 

1.7 (1.1–2.5)

 

   ≥5

1.4 (0.8–2.4)

 

1.8 (1.0–3.6)

 

Religion

 

0.04

 

0.09

   Islam (ref)

1.0

 

1.0

 

   Christian

1.7 (1.0–2.8)

 

1.5 (0.9–2.5)

 

Education

 

0.5

  

   None (ref)

1.0

   

   Quaranic

0.8 (0.1–6.3)

   

   Primary

(0.5–2.7)

   

   Secondary

(0.7–3.4)

   

   Tertiary

1.3 (0.6–2.8)

   

Marital Status

 

0.08

 

1.0

   Single (ref)

1.0

 

1.0

 

   Married

0.5 (0.4–0.8)

 

(0.6–1.2)

 

   Widowed

0.5 (0.3–0.8)

 

(0.6–1.6)

 

   Divorced

0.7 (0.4–1.3)

 

(0.6–1.9)

 

   Cohabiting

0.6 (0.1–4.1)

 

0.6 (0.1–4.1)

 

Occupation

 

0.6

  

   Employed (ref)

1.0

   

   Unemployed

(1.4–4.2)

   

   Student

(0.4–5.5)

   

   Other

1.0 (0.5–2.1)

   

   N/A

1.4 (0.4–5.3)

   

Contraceptive use

1.0 (0.7–1.4)

1.0

  

Hormonal contraceptives

0.6 (0.1–3.8)

0.5

  

Intrauterine devices

1.5 (0.5–4.5)

0.5

  

Barrier contraceptives

1.2 (0.8–1.7)

0.4

  

Clinical characteristics

    

BMI (kg/m2)

 

0.8

  

   <18.5 (ref)

1.0

   

   18.5–24.9

(0.7–1.5)

   

   25–29.9

0.6 (0.2–2.5)

   

   ≥30

1.0 (0.5–1.8)

   

Vaginal wall abnormality

 

0.0006

 

0.0007

   None (ref)

1.0

 

1.0

 

   Other

2.0 (1.3–2.9)

 

1.9 (1.3–2.8)

 

Last CD4 count (per mm3)

 

<0.0001*

 

<0.0001*

   <300 (ref)

1.0

 

1.0

 

   300–<450

0.5 (0.3–0.7)

 

(0.3–0.7)

 

   450–<650

0.5 (0.3–0.7)

 

0.5 (0.3–0.8)

 

   ≥650

0.3 (0.2–0.5)

 

0.3 (0.2–0.6)

 

WHO stage

 

1.0

  

   Stage 1 (ref)

1.0

   

   Stage 2

(0.2–1.4)

   

   Stage 3

1.3 (0.6–2.7)

   

   Stage 4

1.6 (0.2–10.2)

   

ART Regimen currently on

 

0.6

  

   TDF-containing ART

1.4(1.0–2.0)

   

   ZDV-containing ART

(1.0–2.2)

   

   d4T-containing ART

0.9 (0.4–2.1)

   
  1. *p-value for trend using median value of each category.