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Table 4 Timing of events by symptom at presentation for medical care

From: Human influenza A H5N1 in Indonesia: health care service-associated delays in treatment initiation

  Symptom onset to presentation for medical care Presentation for medical care to viral testing Presentation for medical care to antiviral treatment
Symptom noted at first presentation for medical care N Median days (Min, Max) p-value N Median days (Min, Max) p-value N Median days (Min, Max) p-value
Fever 93 0.0 (0.0, 7.0) 0.34 76 6.0 (-4.0, 18.0) 0.21 38 6.5 (1.0, 11.0) 0.11
No fever 8 0.0 (0.0, 2.0)   8 7.5 (1.0, 25.0)   2 9.5 (9.0, 10.0)  
Unexplained respiratory illness 66 0.0 (0.0, 7.0) 0.05 57 6.0 (0.0, 25.0) 0.04 20 7.0 (1.0, 11.0) 0.71
No unexplained respiratory illness 38 0.0 (0.0, 4.0)   32 7.0 (3.0, 18.0)   22 7.0 (2.0, 11.0)  
Excessive sputum 1 0.0 (0.0, 0.0) 0.61 1 7.0 (7.0, 7.0) 0.97 1 7.0 (7.0, 7.0) 0.80
No excessive sputum 50 0.0 (0.0, 7.0)   45 7.0 (0.0, 25.0)   26 8.0 (1.0, 11.0)  
Sore throat/pharyngitis 25 0.0 (0.0, 7.0) 0.06 19 5.0 (-4.0, 11.0) 0.14 12 6.0 (1.0, 11.0) 0.69
No sore throat/pharyngitis 44 0.0 (0.0, 7.0)   42 7.0 (0.0, 25.0)   22 7.0 (2.0, 10.0)  
Rhinorrhea 2 0.5 (0.0, 1.0) 0.73 2 6.5 (6.0, 7.0) 0.77 2 7.5 (7.0, 8.0) 0.83
No rhinorrhea 66 0.0 (0.0, 7.0)   57 6.0 (0.0, 25.0)   33 7.0 (1.0, 11.0)  
Tachypnea 27 1.0 (0.0, 7.0) 0.04 23 5.0 (-4.0, 10.0) < 0.01 6 6.0 (1.0, 11.0) 0.40
No tachypnea 64 0.0 (0.0, 7.0)   57 7.0 (1.0, 25.0)   31 7.0 (2.0, 11.0)  
Cyanosis 0 - N/A 0 - N/A 0 - N/A
No cyanosis 56 0.0 (0.0, 7.0)   49 6.0 (0.0, 11.0)   32 7.0 (2.0, 11.0)  
Abnormal breath sounds 0 - N/A 0 - N/A 0 - N/A
No abnormal breath sounds 40 0.0 (0.0, 5.0)   36 7.0 (0.0, 11.0)   25 8.0 (2.0, 11.0)  
Diarrhea 9 0.0 (0.0, 2.0) 0.43 7 6.0 (3.0, 8.0) 0.70 1 9.0 (9.0, 9.0) 0.47
No diarrhea 70 0.0 (0.0, 7.0)   60 6.0 (0.0, 18.0)   33 7.0 (1.0, 11.0)  
Abdominal pain 14 0.5 (0.0, 7.0) 0.20 11 6.0 (3.0, 9.0) 0.89 5 7.0 (5.0, 9.0) 0.98
No abdominal pain 60 0.0 (0.0, 7.0)   53 6.0 (0.0, 18.0)   32 7.0 (1.0, 11.0)  
Vomiting 11 0.0 (0.0, 1.0) 0.91 8 6.5 (3.0, 10.0) 0.43 4 8.0 (7.0, 9.0) 0.43
No vomiting 70 0.0 (0.0, 7.0)   62 6.0 (0.0, 25.0)   32 7.0 (1.0, 11.0)  
Headache 25 1.0 (0.0, 7.0) < 0.01 21 6.0 (0.0, 9.0) 0.65 8 7.0 (5.0, 10.0) 0.84
No headache 48 0.0 (0.0, 7.0)   41 7.0 (0.0, 25.0)   26 7.5 (1.0, 11.0)  
Neurological involvement 0 - N/A 0 - N/A 0 - N/A
No neurological involvement 53 0.0 (0.0, 7.0)   46 7.0 (0.0, 25.0)   28 7.5 (2.0, 11.0)  
Psychiatric symptoms 0 - N/A 0 - N/A 0 - N/A
No psychiatric symptoms 43 0.0 (0.0, 5.0)   38 7.0 (0.0, 11.0)   27 8.0 (2.0, 11.0)  
Fatigue 11 1.0 (0.0, 4.0) 0.21 10 6.0 (3.0, 7.0) 0.32 4 6.0 (3.0, 7.0) 0.18
No fatigue 58 0.0 (0.0, 7.0)   49 7.0 (0.0, 18.0)   29 7.0 (1.0, 11.0)  
Myalgia 6 0.5 (0.0, 2.0) 0.38 5 7.0 (6.0, 9.0) 0.47 2 6.0 (5.0, 7.0) 0.49
No myalgia 51 0.0 (0.0, 7.0)   43 7.0 (0.0, 11.0)   27 8.0 (1.0, 11.0)  
Bleeding gums or nose 0 - N/A 0 - N/A 0 - N/A
No bleeding gums or nose 80 0.0 (0.0, 7.0)   69 6.0 (-4.0, 25.0)   35 7.0 (1.0, 11.0)  
Enlarged Liver 0 - N/A 0 - N/A 0 - N/A
No enlarged liver 45 0.0 (0.0, 4.0)   37 7.0 (1.0, 11.0)   27 8.0 (2.0, 11.0)  
Conjunctivitis 0 - N/A 0 - N/A 0 - N/A
No conjunctivitis 59 0.0 (0.0, 7.0)   51 7.0 (0.0, 25.0)   30 7.0 (2.0, 11.0)