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Table 2 Univariate and multivariate associations with time from last positive HIV test and initiation of ART

From: Evidence of improving antiretroviral therapy treatment delays: an analysis of eight years of programmatic outcomes in Blantyre, Malawi

Variable

GMR±

95% CI*

Adjusted GMR±

95% CI*

P

Sex

     

  Men

1

 

1

 

0.007

  Women

1.13

1.06-1.21

1.12

1.03-1.22

 

Age group

     

  0-5 years

0.87

0.75-0.99

1.02

0.84-1.24

0.526

  5-15 years

1.16

0.99-1.37

1.14

0.93-1.39

 

  15-25 years

1.00

0.89-1.23

0.93

0.81-1.08

 

  25-35 years

1

 

1

  

  35-45 years

1.00

0.92-1.08

0.96

0.87-1.06

 

  ≥ 45 years

1.00

0.90-1.10

0.96

0.84-1.09

 

Site of HIV test

     

  QECH

1

 

1

  

  Facility other than QECH

1.65

1.54-1.77

1.61

1.47-1.77

<0.001

  Unknown

1.82

1.64-2.02

1.93

1.66-2.24

 

WHO stage at registration

     

  Stage 1 or 2

1

    

  Stage 3 or 4

1.01

0.95-1.08

   

CD4 count (cells/μl)

     

  ≥ 350

1

 

1

 

<0.001

  250 – 350

0.87

0.70-1.11

0.96

0.75-1.20

 

  50 – 250

0.76

0.61-0.95

0.77

0.62-0.98

 

  <50

0.50

0.40-0.63

0.53

0.42-0.68

 

Year of ART initiation

     

  2004

0.92

0.75-1.14

0.79

0.52-1.21

0.004

  2005

1

 

1

  

  2006

0.72

0.60-0.87

0.75

0.48-1.16

 

  2007

0.64

0.55-0.76

0.71

0.50-1.03

 

  2008

0.68

0.59-0.80

0.72

0.51-1.02

 

  2009

0.69

0.59-0.80

0.69

0.49-0.99

 

  2010

0.75

0.64-0.88

0.85

0.60-1.21

 

  2011

0.54

0.47-0.63

0.84

0.59-1.21

 

Number of ART initiators per year (continuous)

1.00

1.00-1.00

   
  1. ±Bootstrapped estimates of geometric mean ratios, adjusted for sex, age group, site of HIV test, CD4 count strata and year of ART initiation.
  2. *Bias corrected accelerated 95% confidence intervals.
  3. GMR Geometric mean ratio, CI confidence interval, QECH Queen Elizabeth Central Hospital.