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Table 2 Multivariate logistic regression analysis of predictors of vertical transmission at Gondar University Referral Hospital, Northwest Ethiopia

From: Mother-to-child transmission of HIV and its predictors among HIV-exposed infants at a PMTCT clinic in northwest Ethiopia

Variables

HIV status

Crude OR (95% CI)

Adjusted OR (95% CI)

 

Positive

Negative

  

Age at enrolment

    

  ≤ 6 weeks

15

338

1.0

1.0

  > 6 weeks

36

120

6.76 (3.57, 12.79)*

2.89 (1.35, 6.21)*

Sex

    

  Male

26

237

0.97 (0.54, 1.73)

**

  Female

25

221

1.0

 

Residence

    

  Urban

27

397

1.0

1.0

  Rural

24

61

5.79 (3.14, 10.67)*

5.05 (2.34, 10.9)*

Place of Birth

    

  Health institution

33

427

1.0

1.0

  Home

18

31

7.5 (3.81, 14.83)

2.82 (1.2, 6.64)

Maternal status

    

  Alive

47

451

1.0

**

  Dead

4

7

5.48 (1.55, 19.42)*

 

Maternal PMTCT intervention

    

  Yes

20

397

1.0

1.0

  No

31

61

10.09 (5.41, 18.82)*

5.02 (2.43, 10.4)*

Infant feeding practice

    

  Exclusive breast feeding

26

371

1.0

1.0

  Exclusive replacement feeding

8

59

1.94 (0.84,4.48)

1.72 (0.65, 4.53)

  Mixed feeding

16

24

9.51 (4.51,20.08)*

4.18 (1.59, 10.99)*

History of infant ARV prophylaxis at birth

    

  Received

21

400

1.0

 

  Not Received

30

44

12.99 (6.86, 24.6)*

**

Infant ARV prophylaxis during follow up

    

  None

30

45

8.22 (2.32, 29.10)*

**

  sdNVP

5

94

0.66 (0.15, 2.89)

 

  sdNVP + AZT 7 days

12

265

0.56 (0.15, 2.07)

 

  sdNVP + AZT 4 weeks

3

37

1.0

 

Baseline Cotrimoxazole

   

**

  Yes

44

364

1.0

 

  No

7

92

0.63 (0.28, 1.44)

 
  1. *Significant at P-Value <0.05.
  2. * *non significant from the multivariate logistic regression (Backward LR method).