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Table 2 Multivariate logistic regression analysis of predictors of vertical transmission at Gondar University Referral Hospital, Northwest Ethiopia

From: Mother-to-child transmission of HIV and its predictors among HIV-exposed infants at a PMTCT clinic in northwest Ethiopia

Variables HIV status Crude OR (95% CI) Adjusted OR (95% CI)
  Positive Negative   
Age at enrolment     
  ≤ 6 weeks 15 338 1.0 1.0
  > 6 weeks 36 120 6.76 (3.57, 12.79)* 2.89 (1.35, 6.21)*
Sex     
  Male 26 237 0.97 (0.54, 1.73) **
  Female 25 221 1.0  
Residence     
  Urban 27 397 1.0 1.0
  Rural 24 61 5.79 (3.14, 10.67)* 5.05 (2.34, 10.9)*
Place of Birth     
  Health institution 33 427 1.0 1.0
  Home 18 31 7.5 (3.81, 14.83) 2.82 (1.2, 6.64)
Maternal status     
  Alive 47 451 1.0 **
  Dead 4 7 5.48 (1.55, 19.42)*  
Maternal PMTCT intervention     
  Yes 20 397 1.0 1.0
  No 31 61 10.09 (5.41, 18.82)* 5.02 (2.43, 10.4)*
Infant feeding practice     
  Exclusive breast feeding 26 371 1.0 1.0
  Exclusive replacement feeding 8 59 1.94 (0.84,4.48) 1.72 (0.65, 4.53)
  Mixed feeding 16 24 9.51 (4.51,20.08)* 4.18 (1.59, 10.99)*
History of infant ARV prophylaxis at birth     
  Received 21 400 1.0  
  Not Received 30 44 12.99 (6.86, 24.6)* **
Infant ARV prophylaxis during follow up     
  None 30 45 8.22 (2.32, 29.10)* **
  sdNVP 5 94 0.66 (0.15, 2.89)  
  sdNVP + AZT 7 days 12 265 0.56 (0.15, 2.07)  
  sdNVP + AZT 4 weeks 3 37 1.0  
Baseline Cotrimoxazole     **
  Yes 44 364 1.0  
  No 7 92 0.63 (0.28, 1.44)  
  1. *Significant at P-Value <0.05.
  2. * *non significant from the multivariate logistic regression (Backward LR method).