Mother-to-child transmission of HIV and its predictors among HIV-exposed infants at a PMTCT clinic in northwest Ethiopia

Table 2 Multivariate logistic regression analysis of predictors of vertical transmission at Gondar University Referral Hospital, Northwest Ethiopia

Variables	HIV status		Crude OR (95% CI)	Adjusted OR (95% CI)
	Positive	Negative
Age at enrolment
≤ 6 weeks	15	338	1.0	1.0
> 6 weeks	36	120	6.76 (3.57, 12.79)*	2.89 (1.35, 6.21)*
Sex
Male	26	237	0.97 (0.54, 1.73)	**
Female	25	221	1.0
Residence
Urban	27	397	1.0	1.0
Rural	24	61	5.79 (3.14, 10.67)*	5.05 (2.34, 10.9)*
Place of Birth
Health institution	33	427	1.0	1.0
Home	18	31	7.5 (3.81, 14.83)	2.82 (1.2, 6.64)
Maternal status
Alive	47	451	1.0	**
Dead	4	7	5.48 (1.55, 19.42)*
Maternal PMTCT intervention
Yes	20	397	1.0	1.0
No	31	61	10.09 (5.41, 18.82)*	5.02 (2.43, 10.4)*
Infant feeding practice
Exclusive breast feeding	26	371	1.0	1.0
Exclusive replacement feeding	8	59	1.94 (0.84,4.48)	1.72 (0.65, 4.53)
Mixed feeding	16	24	9.51 (4.51,20.08)*	4.18 (1.59, 10.99)*
History of infant ARV prophylaxis at birth
Received	21	400	1.0
Not Received	30	44	12.99 (6.86, 24.6)*	**
Infant ARV prophylaxis during follow up
None	30	45	8.22 (2.32, 29.10)*	**
sdNVP	5	94	0.66 (0.15, 2.89)
sdNVP + AZT 7 days	12	265	0.56 (0.15, 2.07)
sdNVP + AZT 4 weeks	3	37	1.0
Baseline Cotrimoxazole				**
Yes	44	364	1.0
No	7	92	0.63 (0.28, 1.44)

*Significant at P-Value <0.05.
* *non significant from the multivariate logistic regression (Backward LR method).