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Table 3 Associations of sex-specific serum GGT and UA quartiles with IFG

From: Serum γ-glutamyltransferase and uric acid levels are associated with impaired fasting glucose in adults from Inner Mongolia, China

 

Subgroup

IFG

OR (95% CI)

 

(n)

n (%)

Model 1

Model 2

Model 3

Males

     

GGT

     

  Q1 (<23 U/L)

312

59 (18.9%)

1 (ref)

1 (ref)

1 (ref)

  Q2 (23–35 U/L)

305

78 (25.6%)

1.62 (1.06–2.50)

1.50 (0.97–2.31)

1.48 (0.94–2.29)

  Q3 (35–57 U/L)

291

94 (32.3%)

0.91 (0.62–1.35)

2.08 (1.32–3.25)

1.99 (1.26–3.15)

  Q4 (>57 U/L)

303

102 (33.7%)

1.01 (0.68–1.51)

2.14 (1.33–3.45)

1.90 (1.16–3.12)

  P for trend

  

0.000

0.001

0.007

UA

     

  Q1 (<296 U/L)

225

71 (31.6%)

1 (ref)

1 (ref)

1 (ref)

  Q2 (296–344 U/L)

236

67 (28.4%)

0.93 (0.61–1.40)

0.84 (0.55–1.27)

0.84 (0.55–1.28)

  Q3 (344–402 U/L)

221

87 (39.4%)

1.43 (0.96–2.13)

1.23 (0.82–1.85)

1.19 (0.79–1.81)

  Q4 (>402 U/L)

194

107 (55.2%)

1.91 (1.28–2.84)

1.52 (1.00–2.31)

1.47 (0.96–2.25)

  P for trend

  

0.000

0.013

0.027

Females

     

GGT

     

  Q1 (<15 U/L)

409

38 (9.3%)

1 (ref)

1 (ref)

1 (ref)

  Q2 (15 ~ 20 U/L)

338

49 (14.5%)

1.76 (1.06–2.94)

1.65 (0.99–2.78)

1.58 (0.94–2.67)

  Q3 (20 ~ 30 U/L)

366

74 (20.2%)

2.69 (1.63–4.45)

2.44 (1.46–4.08)

2.26 (1.33–3.83)

  Q4 (>30 U/L)

370

98 (26.5%)

3.52 (2.17–5.72)

3.19 (1.93–5.27)

2.86 (1.70–4.82)

  P for trend

  

0.000

0.000

0.000

UA

     

  Q1 (<220 U/L)

330

36 (10.9%)

1 (ref)

1 (ref)

1 (ref)

  Q2 (220–262 U/L)

325

42 (12.9%)

1.16 (0.71–1.90)

1.09 (0.66–1.80)

1.08 (0.65–1.78)

  Q3 (262–310 U/L)

298

71 (24.6%)

1.82 (1.15–2.90)

1.69 (1.05–2.71)

1.61 (0.99–2.61)

  Q4 (>310 U/L)

262

108 (41.2%)

2.70 (1.72–4.24)

2.41 (1.52–3.84)

2.22 (1.37–3.58)

  P for trend

  

0.000

0.000

0.000

  1. 1 Abbreviations: GGT, γ-Glutamyltransferase; UA, Uric acid; IFG, Impaired fasting glucose; OR, Odds ratio; CI, Confidence interval.
  2. 2 Multivariate logistic regression models were used to estimate the ORs and 95% CIs.
  3. Model 1: adjusted for age, ethnicity, smoking, alcohol consumption, physical labor.
  4. Model 2: Model 1 plus body mass index, waist circumference, systolic blood pressure, and diastolic blood pressure.
  5. Model 3: Model 2 plus total cholesterol, triglyceride, high-density lipoprotein–cholesterol, and low-density lipoprotein–cholesterol.