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Table 2 Standardized mortality ratios for HCV serological groups vs. BC population

From: Mortality among British Columbians testing for hepatitis C antibody

  

SNR (n=342,325)

MNR (n=73,476)

REAC (n=27,812)

SERO (n=2,408)

All HCV +ve (n=30,220)

ICD-10

Cause of death

SMR (95% CI)

SMR (95% CI)

SMR (95% CI)

SMR (95% CI)

SMR (95% CI)

A00-R99; V01-Y98

All

1.44 (1.41 - 1.46)

2.59 (2.49 - 2.69)

4.68 (4.50 - 4.86)

10.13 (8.39 - 12.12)

4.78 (4.61 - 4.96)

B15-B19; B942; C22; K70-K76

Liver related

3.00 (2.77 - 3.24)

8.44 (7.47 - 9.50)

23.93 (22.03 - 25.95)

14.77 (6.36 - 29.09)

23.73 (21.86 - 25.72)

B15-B19; B942

 Viral hepatitis

1.04 (0.70 - 1.49)

2.12 (1.06 - 3.79)

65.32 (58.51 - 72.70)

40.31 (13.06 - 93.93)

64.73 (58.03 - 71.99)

C22

 Liver cancer

2.64 (2.26 - 3.07)

4.79 (3.46 - 6.48)

17.31 (14.10 - 21.04)

9.02 (0.23 - 50.23)

17.16 (13.99 - 20.83)

K70-K76

 Liver disease

3.68 (3.34 - 4.05)

11.96 (10.43 - 13.65)

11.09 (9.38 - 13.01)

6.52 (0.79 - 23.53)

10.99 (9.31 - 12.88)

K70

  Alcoholic

3.64 (3.15 - 4.20)

8.25 (6.50 - 10.33)

10.58 (8.39 - 13.17)

5.45 (0.14 - 30.37)

10.46 (8.30 - 13.00)

K71-K76

  Non-alcoholic

3.71 (3.25 - 4.21)

15.65 (13.20 - 18.43)

11.69 (9.11 - 14.77)

8.05 (0.20 - 44.85)

11.62 (9.07 - 14.66)

F11-F16; F19; X40-X44; X60-X64; X85; Y10-Y14

Drug related

1.77 (1.56 - 2.00)

4.54 (3.80 - 5.37)

19.94 (18.31 - 21.69)

36.66 (27.12 - 48.46)

20.72 (19.09 - 22.45)

B20-B24

HIV

1.89 (1.48 - 2.37)

4.08 (2.81 - 5.73)

26.70 (23.49 - 30.22)

35.61 (18.94 - 60.89)

27.03 (23.86 - 30.50)

E10-E14

Diabetes

1.86 (1.69 - 2.03)

5.66 (4.84 - 6.57)

2.21 (1.52 - 3.10)

4.49 (0.11 - 24.99)

2.24 (1.55 - 3.13)

N17-N19; I12-I13; N00-N08

Renal failure

2.41 (2.16 - 2.69)

12.96 (11.12 - 15.03)

4.58 (3.07 - 6.59)

14.85 (0.38 - 82.72)

4.69 (3.16 - 6.70)

C00-C97

Malignant neoplasm

1.34 (1.30 - 1.39)

1.71 (1.57 - 1.86)

2.35 (2.13 - 2.59)

2.03 (0.74 - 4.42)

2.34 (2.12 - 2.58)

C22.0; C22.2-C22.9

Hepatocellular carcinoma

5.34 (4.47 - 6.34)

9.58 (6.67 - 13.32)

36.68 (29.85 - 44.62)

17.04 (0.43 - 94.89)

36.27 (29.54 - 44.07)

  1. Data sources: BCCDC Public Health Microbiology and Reference Laboratory, BC Ministry of Health Services, and BC Vital Statistics Agency.
  2. SNR=single non-reactive; MNR=multiple non-reactive; REAC=reactive at first test; SERO=seroconverter; SMR=standardized mortality ratio.