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Table 1 Adolescents reporting problems (EQ-5D), before and 1 year after screening-detected celiac disease diagnosis, compared to referents without celiac disease

From: Health-related quality of life in adolescents with screening-detected celiac disease, before and one year after diagnosis and initiation of gluten-free diet, a prospective nested case-referent study

Dimensions at Baseline and Follow–up Screening-detected CD (casesn = 103) Non CD (referentsn = 483) Odds Ratios (95% CI)a
  n (%) with problems n (%) with problems Bivariate LRb Multivariate LRc
Mobility
  Baseline 3 (2.9) 11 (2.3) 0.78 (0.21-2.84) 1.28 (0.35-4.68)
  Follow-up 1 (1.0) 7 (1.4) 0.67 (0.08-5.48) 0.67 (0.08-5.52)
Self care
  Baseline 0 0 2 (0.4) 0.00 (0.00-) 0.00 (0.00-)
  Follow-up 0 0 2 (0.4) 0.00 (0.00-) 0.00 (0.00-)
Activity
  Baseline 3 (2.9) 13 (2.7) 0.92 (0.26-3.30) 1.09 (0.31-3.91)
  Follow-up 2 (1.9) 11 (2.3) 0.85 (0.19-3.89) 0.85 (0.18-3.88)
Pain
  Baseline 21 (20.4) 95 (19.7) 0.96 (0.56-1.62) 1.18 (0.69-2.02)
  Follow-up 13 (12.6) 106 (21.9) 0.51 (0.28-0.96) 0.50 (0.27-0.94)
Anxiety/Depression
  Baseline 13 (12.6) 52 (10.8) 0.84 (0.44-1.60) 1.37 (0.70-2.69)
  Follow-up 15 (14.6) 95 (19.7) 0.70 (0.39-1.26) 0.65 (0.35-1.20)
  1. a Odds ratio (95% confidence interval).
  2. b Bivariate logistic regression using case/referent and problems reported.
  3. c Multivariate logistic regression using case/referent and problems reported at baseline and problems reported at follow-up.