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Table 2 Prevalence of anti-tuberculosis drug resistance among M. tuberculosis isolates from new and previously treated patients the results of drug susceptibility pattern by type of case

From: Rates and risk factors for drug resistance tuberculosis in Northeastern China

 

New cases n (%)

Previously treated n (%)

Combined n (%)

Total strans tested

816

196

1012

Susceptibility to all drugs

625(76.6)

79(40.3)

704(69.6)

 Susceptibility to fist-line

661(81.0)

85(43.4)

746(73.7)

 Susceptibility to second-line

751(92.0)

155(79.1)

906(89.5)

Any resistance

191(23.4)

117(59.7)

308(30.4)

 H

91(11.2)

93(47.4)

184(18.2)

 R

48(5.9)

66(33.7)

114(11.3)

 E

30(3.7)

42(21.4)

72(7.1)

 S

90(11.0)

51(26.0)

141(13.9)

 K

28(3.4)

14(7.1)

42(4.2)

 O

42(5.1)

36(18.4)

78(7.7)

Mono-resistance

113(13.8)

22(11.2)

135(13.3)

 H only

27(3.3)

8(4.1)

35(3.5)

 R only

11(1.3)

3(1.5)

14(1.4)

 E only

1(0.1)

0

1(0.1)

 S only

42(5.1)

5(2.6)

47(4.6)

 K only

18(2.2)

2(1.0)

20(2.0)

 O only

14(1.7)

4(2.0)

18(1.8)

MDR-TB

34(4.2)

54(27.6)

88(8.7)

 H + R

5(0.6)

13(6.6)

18(1.8)

 H + R + E

2(0.2)

5(2.6)

7(0.7)

 H + R + S

7(0.9)

10(5.1)

17(1.7)

 H + R + K

0

0

0

 H + R + O

2(0.2)

5(2.6)

7(0.7)

 H + R + E + S

7(0.9)

4(2.0)

11(1.1)

 H + R + E + K

0

0

0

 H + R + E + O

4(0.5)

4(2.0)

8(0.8)

 H + R + S + K

1(0.1)

1(0.5)

2(0.2)

 H + R + S + O

2(0.2)

1(0.5)

3(0.3)

 H + R + K + O

0

1(0.5)

1(0.1)

 H + R + E + S + K

0

0

0

 H + R + E + S + O

4(0.5)

6(3.1)

10(1.0)

 H + R + E + K + O

0

1(0.5)

1(0.1)

 H + R + S + K + O

0

1(0.5)

1(0.1)

 H + R + E + S + K + O

0

2(1.0)

2(0.2)

XDR-TB

0

5(2.6)

5(0.5)

  1. H: isoniazid, R: rifampicin, E: ethambutol, S: streptomycin, K: kanamycin and O: ofloxacin. MDR-TB defined as resistance to at least H and R. XDR-TB defined as resistance to at least H, R, K and O.