Explaining the decline in coronary heart disease mortality in Turkey between 1995 and 2008

Unal, Belgin; Sözmen, Kaan; Arık, Hale; Gerçeklioğlu, Gül; Altun, Deniz Utku; Şimşek, Hatice; Doganay, Sinem; Demiral, Yücel; Aslan, Özgür; Bennett, Kathleen; O´Flaherty, Martin; Capewell, Simon; Critchley, Julia

doi:10.1186/1471-2458-13-1135

BMC Public Health

Table 1 Estimated deaths prevented or postponed by medical or surgical treatments in Turkey in 2008

From: Explaining the decline in coronary heart disease mortality in Turkey between 1995 and 2008

						Number of deaths prevented or postponed			Percentage of total reduction
Treatments	Number of eligible patients	Patients receiving treatment (%)	Relative risk reduction (%)	Mean case-fatality (%)	Absolute risk reduction	Best estimate	Minimum estimate	Maximum estimate	Best estimate	Minimum estimate	Maximum estimate
Acute MI	91317			0.067		1677	684	3309	4.7	1.9	9.3
Community CPR	9132	100	0.05	0.067	0.055	443	283	638	1.2	0.8	1.8
Hospital CPR	2740	6	0.32	0.067	0.323	53	34	91	0.1	0.1	0.3
Thrombolysis	91317	29	0.26	0.067	0.014	316	130	656	0.9	0.4	1.8
Aspirin	91317	93	0.15	0.067	0.010	774	317	1420	2.2	0.9	4.0
Beta blocker	91317	70	0.04	0.067	0.003	143	59	296	0.4	0.2	0.8
ACE inhibitor	91317	61	0.07	0.067	0.005	228	93	466	0.6	0.3	1.3
Primary PTCA	91317	18	0.32	0.067	0.020	589	241	1221	1.6	0.7	3.4
Primary CABG	91317	9	0.20	0.067	0.013	112	40	231
MI treatments in 1995 subtracted						-1244	-599	-2367	3.5	1.7	6.6
Unstable angina						639	364	1800	1.8	1.0	5.0
Aspirin & heparin	45658	50	0.33	0.053	0.017	316	129	655	0.9	0.4	1.8
Aspirin alone	45658	88	0.15	0.053	0.008	245	100	465	0.7	0.3	1.3
PG IIB/IIIA	45658	41	0.09	0.053	0.005	70	28	144	0.2	0.1	0.4
CABG surgery for UA	45658	13	0.43	0.053	0.023	107	44	221	0.3	0.1	0.6
PTCA for UA	45658	26	0.32	0.053	0.016	152	62	314	0.4	0.2	0.9
Secondary Prev Post AMI	759071			0.061		4548	1454	6509	12.7	4.1	18.2
Aspirin	759071	73	0.778	0.045	0.007	2170	711	3665	6.1	2.0	10.3
Beta blocker	759071	63	0.526	0.045	0.010	2052	672	3713	5.7	1.9	10.4
ACE inhibitor	759071	61	0.514	0.045	0.009	1771	580	3198	5.0	1.6	9.0
Statin	759071	3	0.757	0.045	0.010	1339	351	2767	3.7	1.0	7.7
Warfarin	759071	8	0.032	0.045	0.010	76	25	138	0.2	0.1	0.4
Secondary Prev Post CABG/PCI	275652			0.006		1752	575	4164	4.9	1.6	11.7
Aspirin	273379	97	0.15	0.017	0.003	496	162	1076	1.4	0.5	3.0
Beta blocker	273379	60	0.23	0.017	0.004	470	154	1167	1.3	0.4	3.3
ACE inhibitor	273379	54	0.20	0.017	0.003	366	120	909	1.0	0.3	2.5
Statin	273379	87	0.22	0.017	0.004	377	124	898	1.1	0.3	2.5
Warfarin	273379	2.2	0.22	0.017	0.004	18	6	44	0.1	0.0	0.1
Rehabilitation	273379					83	27	208	0.2	0.1	0.6
Chronic angina						3348	1105	8627	9.4	3.1	24.2
CABG surgery 1995-2008	103293	100	0.35	0.012	0.002	632	324	1093	1.8	0.9	3.1
CABG treatments in 1995 subtracted	103293					-6	-4	-8	0.0	0.0	-0.1
Angioplasty 1996-2000	103293	100	0.00	0.022	0.000	0	0	0	0.0	0.0	0.0
Aspirin in community	103293	78	0.15	0.012	0.001	2840	931	7066	8.0	2.6	19.8
Statins in community	103293	63	0.23	0.012	0.003	1517	398	4530	4.2	1.1	12.7
Hospital heart failure	46511			0.258		1025	306	2756	2.9	0.9	7.7
ACE inhibitor	46511	43	0.20	0.166	0.033	251	66	744	0.7	0.2	2.1
Beta blocker	46511	37	0.35	0.166	0.058	378	99	1121	1.1	0.3	3.1
Spironolactone	46511	40	0.30	0.166	0.051	510	167	1269	1.4	0.5	3.6
Aspirin	46511	68	0.15	0.166	0.025	428	140	1041	1.2	0.4	2.9
Community heart failure	424611			0.085		2338	747	5961	6.5	2.1	16.7
ACE inhibitor		70	0.20	0.085	0.013	479	126	1430	1.3	0.4	4.0
Beta blocker		70	0.35	0.085	0.030	986	323	2453	2.8	0.9	6.9
Spironolactone		25	0.31	0.085	0.030	883	289	2197	2.5	0.8	6.1
Aspirin		90	0.15	0.085	0.013	924	303	2299	2.6	0.8	6.4
Statins		40	0.00	0.085	0.000	0	0	0	0.0	0.0	0.0
Hypertension treatment	10029567	57	0.13	0.007	0.001	2153	356	4472	6.0	1.0	12.5
Statins for primary prevention	6133187	2	0.35	0.006	0.002	41	11	205	0.1	0.0	0.6
Total treatment						16671	5356	35362	47.0	15.1	100.0

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