Table 1 Selection of ongoing mega-cohort studies in adults
From: Biobanking across the phenome - at the center of chronic disease research
Web site | Cohort study | Country | Country size | Focus | Sample size | Baseline | Biologic samples |
|---|---|---|---|---|---|---|---|
-- | CONOR/HUNT | Norway | 4,9 Mio | Common disease etiology | 185′000 | 1994-1995 | Blood |
Million women study | United Kingdom | 62,3 Mio | Women’s health | 1′300′000 | 1996 - 2001 | Blood, saliva, in a sub-sample | |
EPIC | Europe | 738,2 Mio | Nutrition, life style and cancer other diseases | 520′000 | 1997 | Blood | |
-- | Mexico city prospective study | Mexico | 117,4 Mio | Major determinants of morbidity and premature mortality | 150′000 | 1998-2004 | Blood |
deCODE | Iceland | 0.4 Mio | Research company | 200′000 | 2000 | Various | |
Millennium | USA | 313,3 Mio | US military family cohort | 150′000 | 2001 | Not specified | |
Estonian biobank | Estonia | 1.3 Mio | Biologic resource | 50′000 | 2002 | Blood | |
http://www.birmingham.ac.uk/research/activity/mds/projects/HaPS/PHEB/Guangzhou/index.aspx | Guanghzou Biobank Cohort study | China | 1339,7 Mio | Genetic, lifestyle, occupational and environmental factors, and life course Causes of the common chronic diseases | 40′000 | 2003 | Blood, urine |
China Kandoorie Biobank | China | 1339,7 Mio | Chronic disease etiology, complex interplay of lifestyle, environmental, and genetic susceptibility | 500′000 | 2004-2008 | Blood | |
PURE | Several countries | 3223,7 Mio | Maladaptation to urbanization and cardiovascular health | 120′000 | 2006 | Blood | |
UK biobank | United Kingdom | 62,3 Mio | Common disease etiology | 500′000 | 2007 - 2010 | Blood, saliva, urine | |
LifeLines | The Netherlands | 16,8 Mio | causes and prognosis of burden of disease, co-determinants, rather than comorbidity, family study | 165′000 | 2007 | Blood, urine | |
Nutrinet Santé | France | 65,4 Mio | Nutrition and health | 500′000 | 2009 | Blood, urine | |
The Canadian Partnership for Tomorrow Project (CPTP) | Canada | 34,4 Mio | Cancer and chronic disease etiology | 300′000 | 2009 | Blood | |
Life gene | Sweden | 9,4 Mio | Nealth and lifestyle | 500′000 | 2011 | Blood, urine | |
CONSTANCES | France | 65,4 Mio | Biologic and research resource | 500′000 | 2011 | Blood | |
German national cohort | Germany | 81,8 Mio | Common disease etiology | 200′000 | 2012 | Blood |