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Table 3 Characteristics at enrolment and ART initiation of children attending HIV clinics Tanzania by calendar year group

From: Reviewing progress: 7 year trends in characteristics of adults and children enrolled at HIV care and treatment clinics in the United Republic of Tanzania

 

       All children

Pediatric characteristics by year of enrolment

 
 

       All years

       2005-2007

       2008-2009

       2010-2011

p value for trend

 

       N = 4,699

       N = 1,229

       N = 1,877

       N = 1,593

 
 

n  

(%)  

n  

(%)  

n  

(%)  

n  

(%)  

 

Gender

Female

2479

(52.8)

674

(54.8)

984

(52.4)

821

(51.5)

0.09

Male

2220

(47.2)

555

(45.2)

893

(47.6)

772

(48.5)

 

Age at enrolment (years)

0-1 years

1219

(25.9)

227

(18.5)

491

(26.1)

501

(31.5)

<0.0001

2-4 years

1162

(24.7)

280

(22.8)

479

(25.5)

403

(25.3)

 

5-9 years

1431

(30.5)

413

(33.6)

586

(31.2)

432

(27.1)

 

10-14 years

887

(18.9)

309

(25.1)

321

(17.1)

257

(16.1)

 

Point of entry into HIV care

Point of entry documented

4294

(91.4)

1066

(86.7)

1757

(93.6)

1471

(92.3)

<0.0001

VCT

1908

(44.4)

356

(33.4)

867

(49.3)

685

(46.6)

<0.0001

PMTCT

483

(11.2)

75

(7.0)

188

(10.7)

220

(15.0)

 

Other 1

1903

(44.3)

635

(59.6)

702

(40.0)

566

(38.5)

 

Transferred in

Yes

506

(10.8)

54

(4.4)

249

(13.3)

203

(12.7)

<0.0001

WHO stage at enrolment

WHO stage documented

4017

(85.5)

816

(66.4)

1695

(90.3)

1506

(94.5)

<0.0001

I

836

(20.8)

110

(13.5)

351

(20.7)

375

(24.9)

<0.0001

II

1183

(29.4)

189

(23.1)

477

(28.1)

517

(34.3)

 

III

1291

(32.1)

330

(40.4)

557

(32.9)

404

(26.8)

 

IV

707

(17.6)

187

(22.9)

310

(18.3)

210

(13.9)

 

ART eligibility at enrolment2

Eligible

1936

(41.2)

468

(38.1)

810

(43.2)

658

(41.3)

<0.0001

Not eligible

1447

(30.8)

284

(23.1)

607

(32.3)

556

(34.9)

Unknown eligibility

1316

(28.0)

477

(38.8)

460

(24.5)

379

(23.8)

Started ART

Yes

2599

(55.3)

742

(60.4)

1045

(55.7)

812

(51.0)

<0.0001

Age at ART initiation (years)

0-1 years

690

(26.5)

108

(14.6)

270

(25.8)

312

(38.4)

<0.0001

2-4 years

576

(22.2)

150

(20.2)

249

(23.8)

177

(21.8)

 

5-9 years

799

(30.7)

266

(35.8)

338

(32.3)

195

(24.0)

 
 

10-14 years

534

(20.5)

218

(29.4)

188

(18.0)

128

(15.8)

 

First ART regimen3

Stavudine containing

920

(35.4)

295

(39.8)

413

(39.5)

212

(26.1)

<0.0001

 

Zidovudine containing

1636

(62.9)

440

(59.3)

623

(59.6)

573

(70.6)

 
 

Other4

43

(1.7)

7

(0.9)

9

(0.9)

27

(3.3)

 

CD4+ at enrolment5

Number of children ≥5y

2318

-

722

-

907

-

689

-

 

(cells/μL), children ≥5 years

CD4+ documented

941

(40.6)

282

(39.1)

364

(40.1)

295

(42.8)

0.15

<50

112

(11.9)

35

(12.4)

43

(11.8)

34

(11.5)

0.06

50-99

50

(5.3)

23

(8.2)

11

(3.0)

16

(5.4)

 

100-199

111

(11.8)

39

(13.8)

48

(13.2)

24

(8.1)

 

200-349

134

(14.2)

39

(13.8)

53

(14.6)

42

(14.2)

 

≥350

534

(56.7)

146

(51.8)

209

(57.4)

179

(60.7)

 

CD4+ at ART initiation5, (cells/μL), children ≥5 years

CD4+ documented

660

(28.5)

219

(30.3)

276

(30.4)

165

(23.9)

0.007

<50

111

(16.8)

37

(16.9)

40

(14.5)

34

(20.6)

0.28

50-99

68

(10.3)

28

(12.8)

24

(8.7)

16

(9.7)

 

100-199

138

(20.9)

43

(19.6)

67

(24.3)

28

(17.0)

 
 

200-349

149

(22.6)

55

(25.1)

58

(21.0)

36

(21.8)

 
 

≥350

194

(29.4)

56

(25.6)

87

(31.5)

51

(30.9)

 
  1. 1 Includes TB/HIV clinics, inpatient clinics, outpatient clinics, and Persons Living with HIV associations. 2 Based on WHO 2006 guidelines. 3 As a percentage of those who started ART, stavudine and zidovudine containing regimens were combined with lamivudine and nevirapine or efavirenz. 4 Includes less commonly used drugs in the initial ART regimen like abacavir, tenofovir and protease inhibitors. 5 CD4+ done at any date < 90 days before or < 30 days after date of enrolment/ART initiation with priority given to date before and closest to the enrolment/ART initiation date.