Figure 1

Screenshot of EPIPOI showing pneumonia and influenza mortality data from Brazil (available as an example file on the EPIPOI website). Circles in the map represent the amplitude (size) and timing of peaks (colours) of the seasonal signal of each Brazilian state as obtained with the default program settings. They were automatically calculated when the data were loaded and the detrending option was selected (2nd dropbox menu at upper-right corner). The model (red line over the original time series in grey) was obtained by summing the 12-monthly, 6-monthly and 3-monthly harmonics plus the trend. The central histogram indicates the age-profile of mortality for each month of an average year.