From: Burden of paediatric influenza in Western Europe: a systematic review
Reference, country, and study period | Population | Costs |
---|---|---|
Ehlken et al., 2005 [45], | 3,458 children aged 0-36 months, with LRTI. | Mean (SD) costs (in 2002 euros) per community-acquired, office-based case of confirmed influenza: |
Germany, | Setting: 11 office-based paediatricians and 5 hospitals. | Total cost: €223 (€280) |
Influenza season: 1999 — 2001. | Direct medical cost: €66 (€24) | |
Direct non-medical cost: €12 (€10) | ||
Indirect cost: €145 (€266) | ||
Mean (SD) costs (in 2002 euros) per community-acquired, hospitalised case of confirmed influenza: | ||
Total cost: €2,597 (€1,214) | ||
Direct medical cost: €2,428 (€1,200) | ||
Direct non-medical cost: €58 (€75) | ||
Indirect cost: €110 (€249) | ||
Median (95% CI) annual economic burden (in 2002 euros) due to confirmed influenza: | ||
Community-acquired office-based cases: NA | ||
Community-acquired, hospitalised cases: | ||
Median: €7,530,105 (€5,547,410-€10,011,705) | ||
Nosocomial cases: NA | ||
Esposito et al., 2011 [37], | 6,988 children aged < 14 years with ILI. | Mean (SD) costs (in 2008 euros) of influenza in influenza-positive and influenza-negative children and their households, until resolution of illness: |
Italy, | Confirmed influenza cases: 2,143 (30.7%). | |
Influenza season: November 2008 — April 2009. | Total: €131.70 (€71.40); €89.40 (€65.20); P < 0.001 | |
Setting: ED at a university hospital. | ||
Paediatric examinations: €33.00 (€4.00); €30.60 (€4.20) | ||
Antibiotics: €3.70 (€4.30); €4.40 (€4.90) | ||
Antipyretics: €2.40 (€2.00); €1.90 (€1.40) | ||
Hospitalisation: €22.40 (€238.10); €22.50 (€251.00) | ||
Working days lost by mothers: €47.90 (€90.10); €26.70 (€89.90); P < 0.05 | ||
Working days lost by fathers: €22.30 (€89.70); €3.30 (€39.90); P < 0.05 | ||
Mean (SD) costs of influenza in influenza-positive children with influenza A or influenza B and their households, until resolution of illness: | ||
Total: €142.60 (€74.30); €72.80 (€53.30); P < 0.001 | ||
Paediatric examinations: €33.30 (€4.60); €30.90 (€3.40) | ||
Antibiotics: €3.70 (€3.30); €3.40 (€3.10) | ||
Antipyretics: €2.50 (€2.10); €2.00 (€1.90) | ||
Hospitalisation: €22.40 (€243.40); €14.20 (€216.70) | ||
Working days lost by mothers: €54.40 (€94.80); €16.60 (€61.40); P < 0.05 | ||
Working days lost by fathers: €26.30 (€97.70); €5.70 (€33.30); P < 0.05 | ||
Mean (SD) cost of influenza in influenza-positive children of different age groups (<2 years, 2-5 years, and 6-13 years) and their households, until resolution of illness: | ||
Total: €153.20 (€72.80)a; €148.10 (€83.10)a; €73.90 (€41.90) | ||
Paediatric examinations: €33.50 (€5.60); €32.90 (€4.20); €33.00 (€2.50) | ||
Antibiotics: €3.20 (€3.90); €4.00 (€4.60); €3.30 (€3.90) | ||
Antipyretics: €2.40 (€1.90); €2.30 (€2.20); €2.10 (€2.50) | ||
Hospitalisation: €40.80 (€238.80); €23.90 (€268.90); €11.50 (€153.40) | ||
Working days lost by mothers: €46.70 (€96.40)a; €55.60 (€106.70)a; €19.80 (€49.60) | ||
 |  | Working days lost by fathers: €26.60 (€90.40)a; €29.40 (€111.40)a; €4.20 (€39.10) |