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Table 5 Association between alcohol drinking and CRC by obesity status in Newfoundland, 1999-2003

From: Interaction between alcohol drinking and obesity in relation to colorectal cancer risk: a case-control study in Newfoundland and Labrador, Canada

Alcoholic drink

Not Obese (BMI < 30)

Obese (BMI ≥ 30)

 

Case/Control

ORa & 95% CI

ORb & 95% CI

Case/Control

ORa & 95% CI

ORb & 95% CI

Total sample

503/556

    

199/161

    

Alcohol

*

    

*

    

Non-drinkerc

208/197

1.0

 

1.0

 

62/67

1.0

 

1.0

 

Drinkerc

295/359

0.8

0.6-1.0

0.8

0.6-1.1

137/94

1.6

1.0-2.4 *

2.2

1.2-4.0 *

Types of drinks

**

         

1-2

233/262

0.8

0.7-1.1

0.8

0.6-1.1

102/77

1.4

0.9-2.3

2.0

1.1-3.8 *

3+

62/97

0.6

0.4-0.9 ***

0.7

0.4-1.1

35/17

2.2

1.1-4.4 **

3.4

1.4-8.1 **

# of drinking years

     

*

    

1-19

53/82

0.6

0.4-0.9 *

0.6

0.4-0.9 **

25/29

0.9

0.5-1.8

1.6

0.7-3.7

20-39

166/197

0.8

0.6-1.1

0.8

0.6-1.2

81/49

1.8

1.1-2.9 *

2.5

1.3-5.0 *

40+

76/80

0.9

0.6-1.3

0.9

0.6-1.4

31/16

2.1

1.0-4.2 *

2.6

1.1-6.5 *

P-trend

 

ns

 

ns

    

*

 

# of drinks daily

*

         

1-2

167/232

0.7

0.5-0.9 *

0.7

0.5-1.0 *

74/55

1.5

0.9-2.4

2.3

1.2-4.3 *

3-4

36/47

0.7

0.5-1.2

0.7

0.4-1.2

24/21

1.2

0.6-2.4

1.3

0.5-3.2

5+

92/80

1.1

0.8-1.6

1.0

0.7-1.6

39/18

2.3

1.2-4.5 *

3.7

1.5-9.0 *

P-trend

 

ns

 

ns

    

*

 
  1. aOR unadjusted estimates for alcoholic drink
  2. bOR estimates for alcoholic drink from binary models adjusted for cigarette smoke, age, sex, education, marriage, rural/urban, family history of colorectal cancer, diabetes, cholesterol, aspirin, fruits, laxatives and calcium and random effect of census area
  3. cNon-drinker = non-drinkers and light drinkers who drank less than one drink per day; Drinker = drinkers who ever consumed any alcoholic beverages once a week for 6 months or longer
  4. X 2 or Wald test or Cochran-Armitage test for trend: *P < 0.05 **P < 0.01 ***P < 0.001. Cochran-Armitage test for trend: ns = not significant at 5%