Skip to main content

Table 5 Association between alcohol drinking and CRC by obesity status in Newfoundland, 1999-2003

From: Interaction between alcohol drinking and obesity in relation to colorectal cancer risk: a case-control study in Newfoundland and Labrador, Canada

Alcoholic drink Not Obese (BMI < 30) Obese (BMI ≥ 30)
  Case/Control ORa & 95% CI ORb & 95% CI Case/Control ORa & 95% CI ORb & 95% CI
Total sample 503/556      199/161     
Alcohol *      *     
Non-drinkerc 208/197 1.0   1.0   62/67 1.0   1.0  
Drinkerc 295/359 0.8 0.6-1.0 0.8 0.6-1.1 137/94 1.6 1.0-2.4 * 2.2 1.2-4.0 *
Types of drinks **          
1-2 233/262 0.8 0.7-1.1 0.8 0.6-1.1 102/77 1.4 0.9-2.3 2.0 1.1-3.8 *
3+ 62/97 0.6 0.4-0.9 *** 0.7 0.4-1.1 35/17 2.2 1.1-4.4 ** 3.4 1.4-8.1 **
# of drinking years       *     
1-19 53/82 0.6 0.4-0.9 * 0.6 0.4-0.9 ** 25/29 0.9 0.5-1.8 1.6 0.7-3.7
20-39 166/197 0.8 0.6-1.1 0.8 0.6-1.2 81/49 1.8 1.1-2.9 * 2.5 1.3-5.0 *
40+ 76/80 0.9 0.6-1.3 0.9 0.6-1.4 31/16 2.1 1.0-4.2 * 2.6 1.1-6.5 *
P-trend   ns   ns      *  
# of drinks daily *          
1-2 167/232 0.7 0.5-0.9 * 0.7 0.5-1.0 * 74/55 1.5 0.9-2.4 2.3 1.2-4.3 *
3-4 36/47 0.7 0.5-1.2 0.7 0.4-1.2 24/21 1.2 0.6-2.4 1.3 0.5-3.2
5+ 92/80 1.1 0.8-1.6 1.0 0.7-1.6 39/18 2.3 1.2-4.5 * 3.7 1.5-9.0 *
P-trend   ns   ns      *  
  1. aOR unadjusted estimates for alcoholic drink
  2. bOR estimates for alcoholic drink from binary models adjusted for cigarette smoke, age, sex, education, marriage, rural/urban, family history of colorectal cancer, diabetes, cholesterol, aspirin, fruits, laxatives and calcium and random effect of census area
  3. cNon-drinker = non-drinkers and light drinkers who drank less than one drink per day; Drinker = drinkers who ever consumed any alcoholic beverages once a week for 6 months or longer
  4. X 2 or Wald test or Cochran-Armitage test for trend: *P < 0.05 **P < 0.01 ***P < 0.001. Cochran-Armitage test for trend: ns = not significant at 5%