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Table 3 The unadjusted OR and adjusted OR of CRC and the corresponding 95% CI for total alcoholic drink by cancer location among males and females in the NL population-based case-control study of CRC in 1999-2003

From: Interaction between alcohol drinking and obesity in relation to colorectal cancer risk: a case-control study in Newfoundland and Labrador, Canada

Alcoholic drink Control (N = 717) Colon Cancer Rectal Cancer Colorectal Cancer
   N = 470 ORa & 95% CI ORb & 95% CI N = 232 ORa & 95% CI ORb & 95% CI N = 702 ORa & 95% CI ORb & 95% CI
Alcohol   **         
   Non-drinkerc 264 189 1.0   81 1.0   270 1.0 1.0
   Drinkerc 453 281 0.9 0.7-1.1 1.0 0.7-1.4 151 1.1 0.8-1.5 0.9 0.6-1.3 432 0.9 0.7-1.2 1.0 0.7-1.3
Types of drinks   **         
   1-2 339 213 0.9 0.7-1.1 1.0 0.7-1.3 122 1.2 0.9-1.6 0.9 0.6-1.4 335 1.0 0.8-1.2 1.0 0.7-1.3
   3+ 114 68 0.8 0.6-1.2 1.0 0.7-1.6 29 0.8 0.5-1.3 0.7 0.4-1.3 97 0.8 0.6-1.2 0.9 0.6-1.4
# of drink years           
   1-19 111 58 0.7 0.5-1.1 0.8 0.6-1.3 20 0.6 0.3-1.0 0.5 0.3-0.9* 80 0.7 0.5-0.9* 0.7 0.5-1.0
   20-39 246 154 0.9 0.7-1.2 1.0 0.7-1.5 93 1.2 0.9-1.7 1.0 0.7-1.6 247 1.0 0.8-1.3 1.0 0.8-1.4
   40+ 96 69 1.0 0.7-1.4 1.1 0.7-1.7 38 1.3 0.8-2.0 1.1 0.7-2.0 107 1.1 0.8-1.5 1.1 0.8-1.7
# of drinks daily   *         
   1-2 287 153 0.7 0.6-1.0 0.9 0.7-1.2 88 1.0 0.7-1.4 0.9 0.6-1.3 241 0.8 0.6-1.1 0.9 0.7-1.2
   3-4 68 41 0.8 0.5-1.3 0.9 0.6-1.5 19 0.9 0.5-1.6 0.6 0.3-1.2 60 0.9 0.6-1.3 0.8 0.5-1.3
   5+ 98 87 1.2 0.9-1.8 1.5 0.9-2.2 44 1.5 0.9-2.3 1.1 0.6-1.8 131 1.3 0.9-1.8 1.3 0.9-1.9
  1. aOR unadjusted estimates for alcoholic drink
  2. bOR estimates for alcoholic drink from binary models adjusted for age, sex, rural/urban, education, marriage, family history of colorectal cancer, diabetes, cholesterol, aspirin, fruits, BMI, laxatives and calcium and random effect of census area
  3. cNon-drinker = non-drinkers and light drinkers who drank less than one drink per day; Drinker = drinkers who ever consumed any alcoholic beverages once a week for 6 months or longer
  4. X 2 or Wald test or Cochran-Armitage test for trend: *P < 0.05 **P < 0.01 ***P < 0.001