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Table 3 The unadjusted OR and adjusted OR of CRC and the corresponding 95% CI for total alcoholic drink by cancer location among males and females in the NL population-based case-control study of CRC in 1999-2003

From: Interaction between alcohol drinking and obesity in relation to colorectal cancer risk: a case-control study in Newfoundland and Labrador, Canada

Alcoholic drink

Control (N = 717)

Colon Cancer

Rectal Cancer

Colorectal Cancer

  

N = 470

ORa & 95% CI

ORb & 95% CI

N = 232

ORa & 95% CI

ORb & 95% CI

N = 702

ORa & 95% CI

ORb & 95% CI

Alcohol

 

**

        

   Non-drinkerc

264

189

1.0

 

81

1.0

 

270

1.0

1.0

   Drinkerc

453

281

0.9 0.7-1.1

1.0 0.7-1.4

151

1.1 0.8-1.5

0.9 0.6-1.3

432

0.9 0.7-1.2

1.0 0.7-1.3

Types of drinks

 

**

        

   1-2

339

213

0.9 0.7-1.1

1.0 0.7-1.3

122

1.2 0.9-1.6

0.9 0.6-1.4

335

1.0 0.8-1.2

1.0 0.7-1.3

   3+

114

68

0.8 0.6-1.2

1.0 0.7-1.6

29

0.8 0.5-1.3

0.7 0.4-1.3

97

0.8 0.6-1.2

0.9 0.6-1.4

# of drink years

          

   1-19

111

58

0.7 0.5-1.1

0.8 0.6-1.3

20

0.6 0.3-1.0

0.5 0.3-0.9*

80

0.7 0.5-0.9*

0.7 0.5-1.0

   20-39

246

154

0.9 0.7-1.2

1.0 0.7-1.5

93

1.2 0.9-1.7

1.0 0.7-1.6

247

1.0 0.8-1.3

1.0 0.8-1.4

   40+

96

69

1.0 0.7-1.4

1.1 0.7-1.7

38

1.3 0.8-2.0

1.1 0.7-2.0

107

1.1 0.8-1.5

1.1 0.8-1.7

# of drinks daily

 

*

        

   1-2

287

153

0.7 0.6-1.0

0.9 0.7-1.2

88

1.0 0.7-1.4

0.9 0.6-1.3

241

0.8 0.6-1.1

0.9 0.7-1.2

   3-4

68

41

0.8 0.5-1.3

0.9 0.6-1.5

19

0.9 0.5-1.6

0.6 0.3-1.2

60

0.9 0.6-1.3

0.8 0.5-1.3

   5+

98

87

1.2 0.9-1.8

1.5 0.9-2.2

44

1.5 0.9-2.3

1.1 0.6-1.8

131

1.3 0.9-1.8

1.3 0.9-1.9

  1. aOR unadjusted estimates for alcoholic drink
  2. bOR estimates for alcoholic drink from binary models adjusted for age, sex, rural/urban, education, marriage, family history of colorectal cancer, diabetes, cholesterol, aspirin, fruits, BMI, laxatives and calcium and random effect of census area
  3. cNon-drinker = non-drinkers and light drinkers who drank less than one drink per day; Drinker = drinkers who ever consumed any alcoholic beverages once a week for 6 months or longer
  4. X 2 or Wald test or Cochran-Armitage test for trend: *P < 0.05 **P < 0.01 ***P < 0.001