Table 4 Hazard Ratio (HR) and 95% Confidence Intervals (CI) for risk of all-cause, cancer-specific, and circulatory death, stratified by Charlson Comorbidity index

Comorbidity Index <3

Score=0

1.00

Ref

1.00

Ref

1.00

Ref

1.00

Ref

1.00

Ref

1.00

Ref

1.00

Ref

1.00

Ref

1.00

Ref

Score=1

1.30

1.07, 1.58

0.97

0.70, 1.36

1.47

1.09, 1.98

1.22

0.85, 1.58

1.30

0.91, 1.85

1.12

0.78, 1.60

1.41

1.00, 1.99

0.63

0.29, 1.36

2.15

1.21, 3.72

Score=2

1.85

1.45, 2.38

1.23

0.68, 2.21

2.73

1.68, 4.43

1.53

1.14, 2.00

0.83

0.50, 1.37

2.25

1.40, 3.62

3.05

2.05, 4.52

2.50

0.93, 6.71

4.30

1.94, 9.53

Score=3

3.16

2.03, 4.94

0.64

0.16, 2.50

1.06

0.30, 3.75

3.30

1.94, 5.64

0.63

0.12, 3.27

0.87

0.22, 3.44

1.89

0.52, 6.79

0.52

0.06, 4.84

1.32

0.08, 22.13

Score=4

13.32

6.15, 28.87

17.66

9.86, 31.64

11.27

5.72, 22.22

19.20

9.17, 40.20

P for trend

Comorbidity Index =3

Score=0

1.00

Ref

1.00

Ref

1.00

Ref

1.00

Ref

1.00

Ref

1.00

Ref

1.00

Ref

1.00

Ref

1.00

Ref

Score=1

1.30

1.07, 1.57

1.31

0.87, 1.96

1.15

0.81, 1.62

1.18

0.93, 1.43

1.54

1.00, 2.37

1.43

1.06, 1.92

0.99

0.81, 1.19

0.84

0.43, 1.63

1.08

0.85, 1.39

Score=2

1.98

1.60, 2.44

1.29

0.80, 2.08

2.18

1.63, 2.90

1.81

1.08, 2.19

1.93

0.97, 3.85

1.35

0.99, 1.86

2.47

1.74, 3.50

1.04

0.44, 2.43

2.26

1.58, 3.23

Score=3

2.52

1.99, 3.18

3.27

2.07, 5.17

2.38

1.28, 4.41

3.57

3.57, 9.86

4.36

1.86, 10.23

5.96

2.10, 16.92

3.69

1.81, 7.55

6.66

1.97, 22.50

Score=4

10.22

5.08, 20.58

3.66

1.93, 6.95

16.55

6.66, 41.11

6.23

2.14, 15.81

0.64

0.09, 4.85

9.14

6.71, 12.46

9.36

3.73, 23.52

4.55

1.09, 18.99

P for trend

Comorbidity Index =4

Score=0

1.00

Ref

1.00

Ref

1.00

Ref

1.00

Ref

1.00

Ref

1.00

Ref

1.00

Ref

1.00

Ref

1.00

Ref

Score=1

1.30

1.07, 1.58

0.97

0.70, 1.36

1.47

1.09, 1.98

1.22

0.85, 1.58

0.93

0.56, 1.56

1.07

0.71, 1.62

1.41

1.11, 1.78

1.72

0.88, 3.33

1.25

0.84, 1.86

Score=2

1.85

1.45, 2.38

1.23

0.68, 2.21

2.73

1.68, 4.43

1.53

1.14, 2.00

0.68

0.35, 1.35

2.04

1.29, 3.24

2.16

1.57, 2.98

2.06

0.98, 4.37

2.28

1.42, 3.65

Score=3

3.16

2.03, 4.94

0.64

0.16, 2.50

1.06

0.30, 3.75

3.30

1.94, 5.64

3.51

1.66, 7.44

3.85

1.79, 8.29

1.60

1.02, 2.53

3.04

1.41, 6.53

0.71

0.23, 2.20

Score=4

13.32

6.15, 28.87

17.66

9.86, 31.64

11.27

5.72, 22.22

10.76

5.29, 21.89

14.44

6.11, 34.15

5.85

2.61, 13.09

26.72

7.81, 91.37

P for trend